Thiophene-2-ol, tetrahydro-, acetate

Base Information

• Chemical Name: Thiophene-2-ol, tetrahydro-, acetate
• CAS No.: 1608-66-8
• Molecular Formula: C6H10O2S
• Molecular Weight: 146.21
• Mol file: 1608-66-8.mol

Synonyms:

Chemical Property of Thiophene-2-ol, tetrahydro-, acetate

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thiophene-2-ol, tetrahydro-, acetate

There total 1 articles about Thiophene-2-ol, tetrahydro-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophene (110-01-0) + chloroform (67-66-3,8013-54-5) + diacetyl peroxide (110-22-5) → 1-oxothiolane (1600-44-8) + 2-(acetoxy)tetrahydrothiophene (1608-66-8) + acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8)

Guidance literature:

Reference yield:

2-(acetoxy)tetrahydrothiophene (1608-66-8) + 5-fluoro-2,4-bis(trimethylsilyloxy)pyrimidine (17242-85-2) → 1-(2'-tetrahydrothienyl)-5-fluorouracil (68321-44-8)

Guidance literature:

With sodium iodide; In acetonitrile; for 7h; Yield given; Heating;

DOI:10.1021/jm00380a016

upstream raw materials:

thiophene

chloroform

diacetyl peroxide

Downstream raw materials:

1-(2'-tetrahydrothienyl)-5-fluorouracil