Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]-

Base Information

Chemical Name:Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]-
CAS No.:161536-30-7
Molecular Formula:C18H23N7O4
Molecular Weight:401.425
Hs Code.:
DSSTox Substance ID:DTXSID60439115
Mol file:161536-30-7.mol

Synonyms:161536-30-7;(2R,3R,4S,5R)-2-(6-Amino-2-((4-aminophenethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]-;DTXSID60439115;(2R,3R,4S,5R)-2-(6-amino-2-{[2-(4-aminophenyl)ethyl]amino}-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Suppliers and Price of Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]-

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:401.18115224
Heavy Atom Count:29
Complexity:538

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CCNC2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N)N
Isomeric SMILES:C1=CC(=CC=C1CCNC2=NC(=C3C(=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N)N

Technology Process of Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]-

There total 4 articles about Adenosine, 2-[[2-(4-aminophenyl)ethyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 13472-00-9
p-Aminophenethylamine

: 146-77-0
2-Chloroadenosine

: 161536-30-7
2-[2-(4-aminophenyl)ethylamino]adenosine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; at 140 ℃; for 4h;

Reference yield:

: 2004-07-1
2-Amino-6-chloropurine riboside

: 161536-30-7
2-[2-(4-aminophenyl)ethylamino]adenosine

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / CuI; I₂; isoamyl nitrite / various solvent(s); tetrahydrofuran / 0.5 h / Heating

2: 94 percent / methanolic ammonia / 18 h / 60 °C

3: 2-methoxy-ethanol / 24 h / 125 °C

With copper(l) iodide; ammonia; iodine; isopentyl nitrite; In tetrahydrofuran; 2-methoxy-ethanol; 1: Iodination / 2: ammoniaolysis / 3: Substitution;
DOI:10.1021/jm000287a

Reference yield:

: 313477-85-9
2-iodo-6-chloro-9-(β-D-ribofuranosyl)purine

: 161536-30-7
2-[2-(4-aminophenyl)ethylamino]adenosine

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / methanolic ammonia / 18 h / 60 °C

2: 2-methoxy-ethanol / 24 h / 125 °C

With ammonia; In 2-methoxy-ethanol; 1: ammoniaolysis / 2: Substitution;
DOI:10.1021/jm000287a