2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)-

Base Information

Chemical Name:2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)-
CAS No.:162147-97-9
Molecular Formula:C16H15ClO2S
Molecular Weight:306.813
Hs Code.:
DSSTox Substance ID:DTXSID50449384
Nikkaji Number:J1.891.620G
Mol file:162147-97-9.mol

Synonyms:162147-97-9;2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)-;DTXSID50449384;1-(Phenylsulfinyl)-1-chloro-4-phenyl-2-butanone

Suppliers and Price of 2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:306.0481286
Heavy Atom Count:20
Complexity:333

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCC(=O)C(S(=O)C2=CC=CC=C2)Cl

Technology Process of 2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)-

There total 5 articles about 2-Butanone, 1-chloro-4-phenyl-1-(phenylsulfinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 7205-94-9
chloromethyl phenyl sulfoxide

: 103-25-3
3-phenylpropanoic acid methyl ester

: 162147-97-9
1-chloro-4-phenyl-1-(phenylsulfinyl)-2-butanone

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -65 ℃; for 0.5h;
DOI:10.1016/0040-4020(94)00989-8

Reference yield: 77.0%

: 51620-80-5
4-phenyl-1-(phenylsulfinyl)-2-butanone

: 162147-97-9
1-chloro-4-phenyl-1-(phenylsulfinyl)-2-butanone

Guidance literature:: 4-phenyl-1-(phenylsulfinyl)-2-butanone; With potassium hydride; In tetrahydrofuran; for 0.666667h;

With hexachloroethane; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1248/cpb.51.602

Reference yield:

: 5042-53-5
1-(phenylsulfanyl)acetone

: 162147-97-9
1-chloro-4-phenyl-1-(phenylsulfinyl)-2-butanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 96 percent / 3-chloroperoxybenzoic acid / CH₂Cl₂ / -15 °C

2.1: LDA; HMPA / tetrahydrofuran / 0.5 h / 0 °C

2.2: 78 percent / tetrahydrofuran / 0.5 h / 0 °C

3.1: KH / tetrahydrofuran / 0.67 h

3.2: 77 percent / C₂Cl₆ / tetrahydrofuran / 3 h / 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydride; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.1248/cpb.51.602