Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl-

Base Information

Chemical Name:Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl-
CAS No.:163273-48-1
Molecular Formula:C14H18BrNO
Molecular Weight:296.207
Hs Code.:
DSSTox Substance ID:DTXSID80446588
Nikkaji Number:J1.009.390B
Wikidata:Q82265295

Synonyms:Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl-;163273-48-1;N-(2-Bromophenyl)-N-methylcyclohexanecarboxamide;DTXSID80446588

Suppliers and Price of Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl-

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:295.05718
Heavy Atom Count:17
Complexity:263

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1=CC=CC=C1Br)C(=O)C2CCCCC2

Technology Process of Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl-

There total 2 articles about Cyclohexanecarboxamide, N-(2-bromophenyl)-N-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 615-36-1
2-bromoaniline

: 2719-27-9
cyclohexanylcarbonyl chloride

: 163273-48-1
N-(2-bromophenyl)-N-methylcyclohexanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 0.67 h / 0 - 20 °C

2.1: sodium hydride / tetrahydrofuran / 0.67 h / 0 °C

2.2: 0 - 20 °C

With sodium hydride; triethylamine; In tetrahydrofuran;
DOI:10.1016/j.mcat.2022.112211

Reference yield:

: 102804-51-3
N-(2-bromophenyl)-N-methyl-1-cyclohexene-1-carboxamide

: 102804-54-6
1′-methylspiro[cyclohexane-1,3′-indolin]-2′-one

: 23824-50-2
cyclohexanecarboxylic acid methylphenylamide

: 52514-10-0
5-Methyl-6a,7,8,9,10,10a-hexahydro-5H-phenanthridin-6-one

: Cyclohex-2-enecarboxylic acid (2-bromo-phenyl)-methyl-amide

: 163273-48-1
N-(2-bromophenyl)-N-methylcyclohexanecarboxamide

Guidance literature:: With samarium diiodide; water; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at -18 ℃; Product distribution;
DOI:10.1016/0040-4039(94)02398-U

Reference yield:

: 163273-48-1
N-(2-bromophenyl)-N-methylcyclohexanecarboxamide

: 102804-54-6
1′-methylspiro[cyclohexane-1,3′-indolin]-2′-one

: 23824-50-2
cyclohexanecarboxylic acid methylphenylamide

Guidance literature:: With (1E,4E)-1,5-diphenylpenta-1,4-dien-3-one palladium(II) complex; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In 1,4-dioxane; at 100 ℃; for 4h;
DOI:10.1021/jo980611y