2-Bromoaniline

Base Information Edit

Chemical Name:2-Bromoaniline
CAS No.:615-36-1
Molecular Formula:C6H6BrN
Molecular Weight:172.024
Hs Code.:2903.30
European Community (EC) Number:210-421-3
NSC Number:7086
UNII:VTP98DS78E
DSSTox Substance ID:DTXSID5060645
Nikkaji Number:J94.957D
Wikidata:Q72451403
Mol file:615-36-1.mol

Synonyms:2-bromoaniline;3-bromoaniline

Suppliers and Price of 2-Bromoaniline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromoaniline
5g
$ 55.00

TRC
2-Bromoaniline
25g
$ 75.00

TCI Chemical
2-Bromoaniline >98.0%(GC)(T)
250g
$ 145.00

TCI Chemical
2-Bromoaniline >98.0%(GC)(T)
25g
$ 25.00

SynQuest Laboratories
2-Bromoaniline 99%
50 g
$ 15.00

Sigma-Aldrich
2-Bromoaniline 98%
25g
$ 61.50

Sigma-Aldrich
2-Bromoaniline 98%
5g
$ 27.70

Oakwood
2-Bromoaniline
100g
$ 18.00

Oakwood
2-Bromoaniline
25g
$ 13.00

Oakwood
2-Bromoaniline
5g
$ 10.00

Total 113 raw suppliers

Chemical Property of 2-Bromoaniline Edit

Chemical Property:

Appearance/Colour:clear yellow to red-brown liquid after melting
Vapor Pressure:0.0795mmHg at 25°C
Melting Point:29 °C
Refractive Index:1.617-1.619
Boiling Point:227 °C at 760 mmHg
PKA:2.53(at 25℃)
Flash Point:91.1 °C
PSA：26.02000
Density:1.594 g/cm³
LogP:2.61250
Storage Temp.:2-8°C
Solubility.:0.949g/l
Water Solubility.:Insoluble in water.
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:170.96836
Heavy Atom Count:8
Complexity:74.9

Purity/Quality:

99% ^*data from raw suppliers

2-Bromoaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): T, Xn,
Hazard Codes:T,Xn
Statements: 23/24/25-33-52/53-36/37/38-20/21/22-24/25
Safety Statements: 36/37-45-61-36/37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Amines, Aromatic
Canonical SMILES:C1=CC=C(C(=C1)N)Br
Description O-bromoaniline, m-bromoaniline and p-bromoaniline corresponds to the three isomers of bromoaniline. All of them three are toxic with its toxicity being more severe than chloroanilines. It can be all via percutaneous absorption, being hemolytic and able to cause bladder cancer. It is mainly used for dye raw materials, such as azo dyes, quinazoline dyes and so on. Heating together with glycerol, concentrated sulfuric acid and o-bromonitrobenzene can generate 8-bromoquinoline. The preparation of the three isomers is as follows: Take the corresponding nitroaniline as raw material, have it reacted with sodium nitrite in sulfuric acid, leading to the formation of diazonium salt, followed by reaction with hydrobromic acid under the action of cuprous bromide, leading to the formation of nitrobromobenzene, further subjecting to iron powder reaction in the bromic acid to generate the above three isomers. Take benzene as raw material, under the action of iron powder, have it reacted with bromine to generate bromobenzene. It is then reacted with mixed acid (the mixture of sulfuric acid and nitric acid) to generate o-nitrobenzene and p-nitro bromobenzene (orthoaccounts of 35%; paraaccounts of 65%), so that the two are separated, followed by the same process as method one to generate o-bromoaniline and p-bromoaniline. Take bromoacetanilide as raw material, put it into sodium hydroxide solution; apply water vapor reflux to obtain the bromoaniline.
Uses Organic synthesis intermediates 2-Bromoaniline is used as a corrosion inhibitor, emulsifying and antiseptic agents. It is used in the rubber industry, e.g. diphenylguanidines, phenylenediamines mercaptobenzothiazoles, aniline ketones and etc.

Technology Process of 2-Bromoaniline

There total 59 articles about 2-Bromoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 2593-27-3
o-bromo-N-hydroxybenzamide

: 615-36-1
2-bromoaniline

Guidance literature:: o-bromo-N-hydroxybenzamide; With acetic anhydride; potassium carbonate; In dimethyl sulfoxide; at 50 ℃; for 2h;

With hydrogenchloride; In water; dimethyl sulfoxide; at 0 ℃;
DOI:10.1016/j.tetlet.2014.12.084

Reference yield: 99.0%

: 583-53-9
2,3-dibromobenzene

: 615-36-1
2-bromoaniline

Guidance literature:: With 2-((dicyclohexylphosphino)methyl)-1,3-bis(2,6-diisopropylphenyl)-4,5-dimethyl-1H-imidazol-3-ium iodide; ammonia; palladium diacetate; sodium t-butanolate; In 1,4-dioxane; at 120 ℃; for 24h; under 7500.75 Torr; Autoclave; Inert atmosphere;
DOI:10.1002/chem.201100984