2-Propenoic acid, 3-(2-methylphenyl)-, butyl ester, (2E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-(2-methylphenyl)-, butyl ester, (2E)-
• CAS No.: 163977-61-5
• Molecular Formula: C14H18O2
• Molecular Weight: 218.296
• Mol file: 163977-61-5.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-(2-methylphenyl)-, butyl ester, (2E)-

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-(2-methylphenyl)-, butyl ester, (2E)-

There total 17 articles about 2-Propenoic acid, 3-(2-methylphenyl)-, butyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 2-methylphenyl bromide (95-46-5) → butyl (2E)-3-(2-methylphenyl)acrylate (163977-61-5)

Guidance literature:

With potassium carbonate; [Pd(Cl){2-{OC(Ph)=CH}-6-(3,5-Me₂C₃HN₂)C₅H₃N}]; In 1-methyl-pyrrolidin-2-one; for 12h; Heating;

DOI:10.1002/ejic.200700347

Reference yield: 99.0%

ortho-methylphenyl iodide (615-37-2) + acrylic acid n-butyl ester (141-32-2,9003-49-0) → butyl (2E)-3-(2-methylphenyl)acrylate (163977-61-5)

Guidance literature:

With C₆₈H₉₆Br₂N₂O₈P₂Pd₂; triethylamine; 3,3'-di-tert-butyl-5,5'-dimethoxybiphenyl-2,2'-diyl diisopropylphosphoramidite; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 16h; regioselective reaction; Inert atmosphere;

DOI:10.1002/ejic.201101271

Reference yield: 97.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + N-(2-methylbenzoyl)saccharin (52707-92-3) → butyl (2E)-3-(2-methylphenyl)acrylate (163977-61-5)

Guidance literature:

With palladium dichloride; In 1-methyl-pyrrolidin-2-one; at 160 ℃; for 18h; Inert atmosphere;

DOI:10.1021/acs.joc.6b02294

upstream raw materials:

acrylic acid n-butyl ester

2-methylphenyl bromide

(2-tolyl)tributyltin

hydroxy(dimethyl)(2-methylphenyl)silane