1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]-

Base Information

Chemical Name:1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]-
CAS No.:16459-05-5
Molecular Formula:C15H11ClN2O2
Molecular Weight:286.718
Hs Code.:
DSSTox Substance ID:DTXSID70443844
Wikidata:Q82261814

Synonyms:1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]-;DTXSID70443844;16459-05-5

Suppliers and Price of 1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:286.0509053
Heavy Atom Count:20
Complexity:345

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=CN2C(=O)COC3=CC=C(C=C3)Cl

Technology Process of 1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]-

There total 3 articles about 1H-Benzimidazole, 1-[(4-chlorophenoxy)acetyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 51-17-2,79351-71-6
benzoimidazole

: 4122-68-3
4-chlorophenyloxyacetyl chloride

: 16459-05-5
1-[(4-chloro-phenoxy)-acetyl]-1H-benzoimidazole

Guidance literature:: With polyethylene glycol-400; potassium carbonate; In acetonitrile; for 2h; Ambient temperature;
DOI:10.1080/00397919808003069

Reference yield:

: 122-88-3
4-Chlorophenoxyacetic acid

: 16459-05-5
1-[(4-chloro-phenoxy)-acetyl]-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / ethyl acetate; methanol / 7 h / Heating

2: 76 percent / 4N NaOH / methanol

With sodium hydroxide; thionyl chloride; In methanol; ethyl acetate;

Reference yield:

: 106-48-9,82344-39-6
4-chloro-phenol

: 16459-05-5
1-[(4-chloro-phenoxy)-acetyl]-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH / H₂O / Heating

2: SOCl₂ / ethyl acetate; methanol / 7 h / Heating

3: 76 percent / 4N NaOH / methanol

With sodium hydroxide; thionyl chloride; In methanol; water; ethyl acetate;