Ethyl tetrahydro-2-methyl-5-oxofuran-2-acetate

Base Information

• Chemical Name: Ethyl tetrahydro-2-methyl-5-oxofuran-2-acetate
• CAS No.: 16807-50-4
• Molecular Formula: C9H14 O4
• Molecular Weight: 186.208
• Hs Code.: 2932190090
• European Community (EC) Number: 240-836-5
• DSSTox Substance ID: DTXSID90937432
• Nikkaji Number: J236.856K
• Mol file: 16807-50-4.mol

Synonyms:16807-50-4;ethyl 2-(2-methyl-5-oxooxolan-2-yl)acetate;Ethyl tetrahydro-2-methyl-5-oxofuran-2-acetate;EINECS 240-836-5;SCHEMBL24157975;DTXSID90937432;Ethyl (2-methyl-5-oxooxolan-2-yl)acetate;Tetrahydro-2-methyl-5-oxofuran-2-acetic acid ethyl ester

Chemical Property of Ethyl tetrahydro-2-methyl-5-oxofuran-2-acetate

Chemical Property:

• Vapor Pressure: 0.00245mmHg at 25°C
• Boiling Point: 287.7°Cat760mmHg
• Flash Point: 142.1°C
• PSA: 52.60000
• Density: 1.103g/cm³
• LogP: 1.03530
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 186.08920892
• Heavy Atom Count: 13
• Complexity: 224

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CC1(CCC(=O)O1)C

Technology Process of Ethyl tetrahydro-2-methyl-5-oxofuran-2-acetate

There total 3 articles about Ethyl tetrahydro-2-methyl-5-oxofuran-2-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl bromoacetate (105-36-2) + 4-oxopentanoic acid ethyl ester (539-88-8) → (2-methyl-5-oxo-tetrahydro-furan-2-yl)-acetic acid ethyl ester (16807-50-4)

Guidance literature:

With toluene; zinc;

Reference yield:

ethyl bromoacetate (105-36-2) + 4-oxopentanoic acid ethyl ester (539-88-8) → (2-methyl-5-oxo-tetrahydro-furan-2-yl)-acetic acid ethyl ester (16807-50-4)

Guidance literature:

Reference yield:

→ (2-methyl-5-oxo-tetrahydro-furan-2-yl)-acetic acid ethyl ester (16807-50-4)

Guidance literature:

B. s. bei β-Oxy-β-methyl-adipinsaeure, Bd. III, S. 454;

upstream raw materials:

ethyl bromoacetate

4-oxopentanoic acid ethyl ester

Downstream raw materials:

3-methyl-3-phenyladipic acid