Benzamide, N,N-bis(3-aminopropyl)-

Base Information

• Chemical Name: Benzamide, N,N-bis(3-aminopropyl)-
• CAS No.: 1652-93-3
• Molecular Formula: C₁₃H₂₁N₃O
• Molecular Weight: 235.329
• DSSTox Substance ID: DTXSID30441785
• Wikidata: Q82258724
• Mol file: 1652-93-3.mol

Synonyms:Benzamide, N,N-bis(3-aminopropyl)-;1652-93-3;DTXSID30441785

Chemical Property of Benzamide, N,N-bis(3-aminopropyl)-

Chemical Property:

• XLogP3: -0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 235.168462302
• Heavy Atom Count: 17
• Complexity: 207

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)N(CCCN)CCCN

Technology Process of Benzamide, N,N-bis(3-aminopropyl)-

There total 3 articles about Benzamide, N,N-bis(3-aminopropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-bis(3-((E)-2-hydroxybenzylideneamino)propyl)benzamide (1380423-35-7) → N,N-bis(3-aminopropyl)benzamide (1652-93-3)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2012.04.070

Reference yield:

bis(3-aminopropyl)amine (56-18-8) → N,N-bis(3-aminopropyl)benzamide (1652-93-3)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 20 °C / Inert atmosphere

2: triethylamine / ethanol / 20 °C

3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

With triethylamine; trifluoroacetic acid; In methanol; ethanol; dichloromethane;

DOI:10.1016/j.tetlet.2012.04.070

Reference yield:

2,2′-((1E,1′E)-((azanediylbis(propane-3,1-diyl))bis-(azanylylidene))-bis(methanylylidene))-diphenol (52279-45-5) → N,N-bis(3-aminopropyl)benzamide (1652-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / ethanol / 20 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

With triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;

DOI:10.1016/j.tetlet.2012.04.070

upstream raw materials:

bis(3-aminopropyl)amine

N,N-bis(3-((E)-2-hydroxybenzylideneamino)propyl)benzamide

2,2′-((1E,1′E)-((azanediylbis(propane-3,1-diyl))bis-(azanylylidene))-bis(methanylylidene))-diphenol