2-acetylcyclododecanone

Base Information

• Chemical Name: 2-acetylcyclododecanone
• CAS No.: 1686-92-6
• Molecular Formula: C14H24O2
• Molecular Weight: 224.343
• Mol file: 1686-92-6.mol

Synonyms:

Chemical Property of 2-acetylcyclododecanone

Chemical Property:

• PSA: 34.14000
• LogP: 3.67530

Purity/Quality:

95% ^*data from raw suppliers

2-ACETYL-CYCLODODECANONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-acetylcyclododecanone

There total 1 articles about 2-acetylcyclododecanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chlorocyclododecanone (35951-28-1) → 2-acetylcyclododecan-1-one (1686-92-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 70 h / 70 °C / Inert atmosphere; Sealed tube

2: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

With sodium hydride; In tetrahydrofuran; acetone; 2: |Eschenmoser Sulfide Contraction;

DOI:10.1016/j.tet.2019.130552

Reference yield: 7.0%

2-phenylethanol (60-12-8) + 2-acetylcyclododecan-1-one (1686-92-6) → 2-phenylethyl 13-oxotetradecanoate (1241621-65-7) + acetic acid phenethyl ester (103-45-7)

Guidance literature:

With indium(III) triflate; at 80 ℃; for 24h; Neat (no solvent); Inert atmosphere;

DOI:10.1002/asia.200900553

upstream raw materials:

2-chlorocyclododecanone

Downstream raw materials:

2-phenylethyl 13-oxotetradecanoate

acetic acid phenethyl ester