civetic acid

Base Information

• Chemical Name: civetic acid
• CAS No.: 1975-86-6
• Molecular Formula: C17H32O2
• Molecular Weight: 268.43
• Mol file: 1975-86-6.mol

Synonyms:

Chemical Property of civetic acid

Chemical Property:

• Melting Point: 26.25°C (estimate)
• Refractive Index: 1.4581 (estimate)
• Boiling Point: 386.37°C (estimate)
• Density: 0.8906 (rough estimate)

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of civetic acid

There total 16 articles about civetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

heptadec-8c-enal (56797-41-2) → 8(Z)-heptadecenoic acid (7432-41-9,1975-86-6)

Guidance literature:

With jones reagent; In acetone; Ambient temperature;

Reference yield:

oleic acid,hydroxy (56472-29-8) → 8(Z)-heptadecenoic acid (7432-41-9,1975-86-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / Pb(OAc)4 / benzene / 0.83 h / 25 °C

2: NaClO₂, NaH₂PO₄*H₂O, 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O / 0.25 h / 25 °C

With lead(IV) acetate; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; benzene;

DOI:10.1021/ja954064z

Reference yield:

1-decyne (764-93-2) → 8(Z)-heptadecenoic acid (7432-41-9,1975-86-6)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) LiNH₂, dioxane, (ii) /BRN= 1280128/

2: (i) aq. EtOH, (ii) NaOH

3: H₂ / Raney-Ni / methanol; pyridine

With hydrogen; nickel; In pyridine; methanol;

upstream raw materials:

2-methyl-nonadec-10-en-2-ol

Elaidic acid

8(Z)-heptadecenoic acid

Methyl oleate

Downstream raw materials:

8E-heptadecenoic acid

3-<(7Z)-hexadecenyl>-4-methylfuran-2,5-dione

Refernces

• 1、 Patterson, Jean E.,Ollmann, Ian R.,Cravatt, Benjamin F.,Boger, Dale L.,Wong, Chi-Huey,Lerner, Richard A.. "Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide". . p. 5938 - 5945. Retrieved 2007/10/03.