Technology Process of Cyclopropaneoctanoic acid, 2-hexyl-, cis-
There total 3 articles about Cyclopropaneoctanoic acid, 2-hexyl-, cis- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: diethylzinc; trifluoroacetic acid / hexane; dichloromethane / 0.33 h / 0 °C / Inert atmosphere
1.2: 1 h / 0 - 20 °C / Inert atmosphere
2.1: lithium hydroxide / methanol; tetrahydrofuran; water / 24 h / 20 °C
With
diethylzinc; trifluoroacetic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; hexane; dichloromethane; water;
DOI:10.1021/acs.orglett.9b01914
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol; toluene; diethyl ether / 0.5 h / 0 - 20 °C
2.1: diethylzinc; trifluoroacetic acid / hexane; dichloromethane / 0.33 h / 0 °C / Inert atmosphere
2.2: 1 h / 0 - 20 °C / Inert atmosphere
3.1: lithium hydroxide / methanol; tetrahydrofuran; water / 24 h / 20 °C
With
diethylzinc; trifluoroacetic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; water; toluene;
DOI:10.1021/acs.orglett.9b01914