Dehydroxy BroMocelecoxib

Base Information

Chemical Name:Dehydroxy BroMocelecoxib
CAS No.:170570-75-9
Molecular Formula:C17H13BrF3N3O2S
Molecular Weight:460.274
Hs Code.:

Synonyms:Dehydroxy Bromocelecoxib;

Suppliers and Price of Dehydroxy BroMocelecoxib

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Dehydroxy Bromocelecoxib
50mg
$ 425.00

TRC
DehydroxyBromocelecoxib
500mg
$ 1100.00

Medical Isotopes, Inc.
DehydroxyBromocelecoxib
50 mg
$ 625.00

Total 5 raw suppliers

Chemical Property of Dehydroxy BroMocelecoxib

Chemical Property:

PSA：86.36000
LogP:5.88150
Solubility.:Chloroform, DCM

Purity/Quality:

NLT 98% ^*data from raw suppliers

Dehydroxy Bromocelecoxib ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Dehydroxy Bromocelecoxib is an intermediate in the synthesis of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor with known anti-inflammatory properties.

Technology Process of Dehydroxy BroMocelecoxib

There total 4 articles about Dehydroxy BroMocelecoxib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 169590-42-5,194044-54-7
4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide

: 170570-75-9
4-[5-(4-bromomethylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In benzene; for 3.5h; UV-irradiation;
DOI:10.1016/j.bmc.2008.10.001

Reference yield:

: 720-94-5
4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

: 170570-75-9
4-[5-(4-bromomethylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / ethanol / 20 h / Heating

2: NBS / benzene / 3 h / Irradiation

With N-Bromosuccinimide; In ethanol; benzene;
DOI:10.1021/jm960803q

Reference yield:

: 17852-52-7,27918-19-0
4-hydrazinobenzene-1-sulfonamide hydrochloride

: 170570-75-9
4-[5-(4-bromomethylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / ethanol / 20 h / Heating

2: NBS / benzene / 3 h / Irradiation

With N-Bromosuccinimide; In ethanol; benzene;
DOI:10.1021/jm960803q