Carbonic acid, 1-(4-bromophenyl)-2-propenyl methyl ester

Base Information

• Chemical Name: Carbonic acid, 1-(4-bromophenyl)-2-propenyl methyl ester
• CAS No.: 170938-18-8
• Molecular Formula: C11H11BrO3
• Molecular Weight: 271.111
• Mol file: 170938-18-8.mol

Synonyms:

Chemical Property of Carbonic acid, 1-(4-bromophenyl)-2-propenyl methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbonic acid, 1-(4-bromophenyl)-2-propenyl methyl ester

There total 4 articles about Carbonic acid, 1-(4-bromophenyl)-2-propenyl methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-(p-bromophenyl)prop-2-en-1-ol (58824-56-9) + methyl chloroformate (79-22-1) → 1-(4'-bromophenyl)-prop-2-enyl methyl carbonate (170938-18-8)

Guidance literature:

With pyridine; In dichloromethane; for 18h; Heating;

DOI:10.1016/0040-4020(95)00481-M

Reference yield: 58.0%

vinyl magnesium bromide (1826-67-1) + 4-bromo-benzaldehyde (1122-91-4) + methyl chloroformate (79-22-1) → 1-(4'-bromophenyl)-prop-2-enyl methyl carbonate (170938-18-8)

Guidance literature:

vinyl magnesium bromide; 4-bromo-benzaldehyde; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

methyl chloroformate; With pyridine; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1002/anie.201710940

Reference yield:

4-bromo-benzaldehyde (1122-91-4) → 1-(4'-bromophenyl)-prop-2-enyl methyl carbonate (170938-18-8)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 2.5 h / 0 - 20 °C / Inert atmosphere

2: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

With pyridine; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1021/acs.orglett.7b02482

upstream raw materials:

1-(p-bromophenyl)prop-2-en-1-ol

methyl chloroformate

4-bromo-benzaldehyde

vinyl magnesium bromide

Downstream raw materials:

(E)-(3-(4-bromophenyl)allyl)(trifluoromethyl)sulfane