1-(Bromomethyl)-2-(methoxymethyl)benzene

Base Information

• Chemical Name: 1-(Bromomethyl)-2-(methoxymethyl)benzene
• CAS No.: 171055-42-8
• Molecular Formula: C9H11BrO
• Molecular Weight: 215.09
• European Community (EC) Number: 832-733-4
• DSSTox Substance ID: DTXSID50601425
• Wikidata: Q82498077
• Mol file: 171055-42-8.mol

Synonyms:1-(bromomethyl)-2-(methoxymethyl)benzene;171055-42-8;2-Methoxymethylbenzyl bromide;SCHEMBL4979415;DTXSID50601425;JQIZZNGLTGKXOD-UHFFFAOYSA-N;MFCD21267524;AKOS014931779;DB-097625;CS-0249258;EN300-4291426

Chemical Property of 1-(Bromomethyl)-2-(methoxymethyl)benzene

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 213.99933
• Heavy Atom Count: 11
• Complexity: 106

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC1=CC=CC=C1CBr

Technology Process of 1-(Bromomethyl)-2-(methoxymethyl)benzene

There total 6 articles about 1-(Bromomethyl)-2-(methoxymethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(methoxymethyl)-benzyl alcohol (62172-88-7) → 2-methoxymethylbenzyl bromide (171055-42-8)

Guidance literature:

With pyridine; sulfurous dibromide; chloroform;

DOI:10.1039/jr9540002819

Reference yield:

1-bromo-2-(methoxymethyl)benzene (52711-30-5) → 2-methoxymethylbenzyl bromide (171055-42-8)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine

2: aq.-ethanolic NaOH

3: LiAlH₄; diethyl ether

4: SOBr₂; pyridine; CHCl₃

With pyridine; sodium hydroxide; lithium aluminium tetrahydride; sulfurous dibromide; diethyl ether; chloroform;

DOI:10.1039/jr9540002819

Reference yield:

2-(bromomethyl)benzoyl bromide (40819-28-1) → 2-methoxymethylbenzyl bromide (171055-42-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium methylate

2: LiAlH₄; diethyl ether

3: SOBr₂; pyridine; CHCl₃

With pyridine; lithium aluminium tetrahydride; sulfurous dibromide; diethyl ether; chloroform; sodium methylate;

DOI:10.1039/jr9540002819

upstream raw materials:

2-(methoxymethyl)-benzyl alcohol

1-bromo-2-(methoxymethyl)benzene

2-(bromomethyl)benzoyl bromide

benzoic acid 2-methoxy-methyl ester

Downstream raw materials:

dimethyl 2-methoxymethylbenzylphosphonate

Refernces

• 1、 -. "1-PHENYLALKYL-PIPERAZINES". Page 77-78. . Retrieved 2010/02/04.