Bis[4-(dimethylamino)phenyl]phosphinic acid

Base Information

• Chemical Name: Bis[4-(dimethylamino)phenyl]phosphinic acid
• CAS No.: 7439-52-3
• Molecular Formula: C16H21N2O2P
• Molecular Weight: 304.329
• NSC Number: 45824
• DSSTox Substance ID: DTXSID00286448
• Wikidata: Q82022175
• Mol file: 7439-52-3.mol

Synonyms:7439-52-3;Bis[4-(dimethylamino)phenyl]phosphinic acid;Bis[p-dimethylaminophenyl]phosphinic acid;DTXSID00286448;TUEYLMCGFMKWBE-UHFFFAOYSA-N;NSC45824;NSC-45824;Bis[4-(dimethylamino)phenyl]phosphinic acid #

Chemical Property of Bis[4-(dimethylamino)phenyl]phosphinic acid

Chemical Property:

• Vapor Pressure: 2.48E-12mmHg at 25°C
• Boiling Point: 536.3°C at 760 mmHg
• Flash Point: 278.1°C
• Density: 1.21g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 304.13406491
• Heavy Atom Count: 21
• Complexity: 339

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)P(=O)(C2=CC=C(C=C2)N(C)C)O

Technology Process of Bis[4-(dimethylamino)phenyl]phosphinic acid

There total 9 articles about Bis[4-(dimethylamino)phenyl]phosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

bis-(4-dimethylamino-phenyl)-hydroxyphosphine (7498-47-7) + 2,2,3,3-Tetrachloro-4-p-chlorophenylsulfonylimino-1,2,3,4-tetrahydronaphthalen-1-one → bis(p-(dimethylamino)phenyl)phosphonic acid (7439-52-3) + C32H29Cl3N3O4PS

Guidance literature:

In benzene; Heating;

Reference yield: 35.0%

bis-(4-dimethylamino-phenyl)-hydroxyphosphine (7498-47-7) + 2,3,5,6-Tetrachloro-N-phenylsulfonyl-1,4-benzoquinonemonoimine (141481-36-9) → bis(p-(dimethylamino)phenyl)phosphonic acid (7439-52-3) + 2,3,5,6-tetrachloro-4-phenylsulfonylaminophenol (330212-89-0) + N-{1-[bis-(4-dimethylamino-phenyl)-phosphinoyl]-2,3,5,6-tetrachloro-4-oxo-cyclohexa-2,5-dienyl}-benzenesulfonamide + C28H26Cl4N3O4PS

Guidance literature:

In benzene; Heating;

Reference yield: 32.0%

N,N′-(cyclohexa-2,5-diene-1,4-diylidene)bis-(4-methylbenzenesulfonamide) (50931-32-3,76165-44-1,76165-45-2) + bis-(4-dimethylamino-phenyl)-hydroxyphosphine (7498-47-7) → bis(p-(dimethylamino)phenyl)phosphonic acid (7439-52-3) + N,N'-ditosyl-p-phenylenediamine (41595-29-3) + C36H39N4O5PS2

Guidance literature:

In benzene; Heating;

upstream raw materials:

bis[4-(N,N-dimethylaminephenyl)]phosphine oxide

bis-(4-dimethylamino-phenyl)-hydroxyphosphine

N,N-dimethyl-aniline

trichlorophosphate

Downstream raw materials:

Di-(4-N.N'-dimethylamino-phenyl)-phosphinsaeure-methyleseter

bis-(4-dimethylaminophenyl)phosphine

phosphoric acid

N,N-dimethyl-aniline