2'-Hydroxyformononetin

Base Information

Chemical Name:2'-Hydroxyformononetin
CAS No.:1890-99-9
Molecular Formula:C16H12 O5
Molecular Weight:284.268
Hs Code.:2914509090
ChEMBL ID:CHEMBL253514
DSSTox Substance ID:DTXSID30415062
Metabolomics Workbench ID:22219
Nikkaji Number:J413.187H
Wikidata:Q23055344
Mol file:1890-99-9.mol

Synonyms:2'-Hydroxyformononetin;Xenognosin B;1890-99-9;2'-Hydroformononetin;2',7-dihydroxy-4'-methoxyisoflavone;2-HYDROXYFORMONONETIN;7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)chromen-4-one;CHEBI:17678;7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-4H-chromen-4-one;C02920;SCHEMBL72611;CHEMBL253514;DTXSID30415062;XKHHKXCBFHUOHM-UHFFFAOYSA-N;4H-1-Benzopyran-4-one, 7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-;LMPK12050081;7,2'-Dihydroxy-4'-methoxyisoflavone;Q23055344;7-hydroxy-3-(2-hydroxy-4-methoxy-phenyl)-chromen-4-one

Suppliers and Price of 2'-Hydroxyformononetin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2''-Hydroxyformononetin
50mg
$ 400.00

TRC
2''-Hydroxyformononetin
100mg
$ 780.00

Biosynth Carbosynth
2'-Hydroxyformononetin
1 mg
$ 640.00

Biosynth Carbosynth
2'-Hydroxyformononetin
0.5 mg
$ 330.00

American Custom Chemicals Corporation
2'-HYDROXYFORMONONETIN 98.00%
1G
$ 7245.00

AK Scientific
2'-Hydroxyformononetin
1mg
$ 914.00

Total 13 raw suppliers

Chemical Property of 2'-Hydroxyformononetin

Chemical Property:

Boiling Point:532.5°Cat760mmHg
Flash Point:204°C
PSA：79.90000
Density:1.42g/cm³
LogP:2.87980
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:284.06847348
Heavy Atom Count:21
Complexity:432

Purity/Quality:

98%,99%, ^*data from raw suppliers

2''-Hydroxyformononetin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O
Uses 2''-Hydroxyformononetin is an intermediate in synthesizing Vestitone (V128900) reductase catalyzes a stereospecific NADPH-dependent reduction of (3R)-vestitone in the bio sysnthesis of antimicrobial isoflavonoid phytoalexin medicarpin.

Technology Process of 2'-Hydroxyformononetin

There total 9 articles about 2'-Hydroxyformononetin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1891-01-6
3-(2,4-dimethoxyphenyl)-7-hydroxy-4H-chromen-4-one

: 1890-99-9
7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: With aluminium trichloride; In acetonitrile; for 3h; Heating;

Reference yield:

: 6496-89-5
2,4-dimethoxyphenylacetic acid

: 1890-99-9
7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: boron trifluoride diethyl etherate / 2 h / 90 - 100 °C

1.2: 50 - 90 °C

2.1: aluminum (III) chloride / acetonitrile / 0 °C / Reflux

2.2: Cooling with ice

With aluminum (III) chloride; boron trifluoride diethyl etherate; In acetonitrile; 1.1: |Friedel-Crafts Acylation;
DOI:10.1039/c2ob25722j

Reference yield:

: 108-46-3
recorcinol

: 1890-99-9
7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: boron trifluoride diethyl etherate / 2 h / 90 - 100 °C

1.2: 50 - 90 °C

2.1: aluminum (III) chloride / acetonitrile / 0 °C / Reflux

2.2: Cooling with ice

With aluminum (III) chloride; boron trifluoride diethyl etherate; In acetonitrile; 1.1: |Friedel-Crafts Acylation;
DOI:10.1039/c2ob25722j