3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole

Base Information

Chemical Name:3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole
CAS No.:55983-75-0
Molecular Formula:C11H9 Cl N2 O3
Molecular Weight:252.657
Hs Code.:
Mol file:55983-75-0.mol

Synonyms:3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole

Suppliers and Price of 3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(3-Chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylicacid 97%
10g
$ 1414.00

Crysdot
1-(3-Chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylicacid 97%
5g
$ 1107.00

Crysdot
1-(3-Chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylicacid 97%
1g
$ 436.00

Total 4 raw suppliers

Chemical Property of 3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole

Chemical Property:

Vapor Pressure:7.26E-09mmHg at 25°C
Boiling Point:449.5°Cat760mmHg
PKA:3.71±0.10(Predicted)
Flash Point:225.6°C
PSA：64.35000
Density:1.42g/cm³
LogP:2.23250

Purity/Quality:

99% ^*data from raw suppliers

1-(3-Chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole

There total 3 articles about 3-carboxy-1-(3-chlorophenyl)-5-methoxypyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1195985-62-6
methyl 1-(3-chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylate

: 55983-75-0
1-(3-chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 50 ℃; for 5h;
DOI:10.1021/jm9012278

Reference yield:

: 1195985-61-5
methyl 1-(3-chlorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate

: 55983-75-0
1-(3-chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / benzene / 0 - 20 °C

2: water; lithium hydroxide / tetrahydrofuran / 5 h / 50 °C

With di-isopropyl azodicarboxylate; water; triphenylphosphine; lithium hydroxide; In tetrahydrofuran; benzene; 1: Mitsunobu reaction;
DOI:10.1021/jm9012278