4-(5-formylthiophen-2-yl)benzoic Acid

Base Information

Chemical Name:4-(5-formylthiophen-2-yl)benzoic Acid
CAS No.:174623-07-5
Molecular Formula:C12H8O3S
Molecular Weight:232.26
Hs Code.:2934999090
European Community (EC) Number:694-828-5
DSSTox Substance ID:DTXSID80405453
Wikidata:Q82210016
Mol file:174623-07-5.mol

Synonyms:174623-07-5;4-(5-formylthiophen-2-yl)benzoic Acid;4-(5-Formyl-thiophen-2-yl)-benzoic acid;4-(5-formyl-2-thienyl)benzoic acid;Benzoic acid, 4-(5-formyl-2-thienyl)-;MFCD06740281;5-(p-Carboxyphenyl)-2-thiophenealdehyde;SCHEMBL2015912;DTXSID80405453;NRGPPHJDPPKYKN-UHFFFAOYSA-N;AKOS004113932;AS-2082;4-(5-Formyl-thiophen-2-yl)-benzoicacid;SY320410;4-(5-formyl-thiophene-2-yl)-benzoic acid;4-(5-Formyl-2-thienyl)benzoic acid, 97%;BB 0222862;CS-0216333;EN300-399089;A911712;4-(5-formyl-thiophen-2-yl)-benzoic acid, AldrichCPR;Z2049898069

Suppliers and Price of 4-(5-formylthiophen-2-yl)benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(5-Formyl-2-thienyl)benzoic acid
100mg
$ 45.00

TRC
4-(5-Formyl-2-thienyl)benzoic acid
500mg
$ 105.00

Sigma-Aldrich
4-(5-Formyl-2-thienyl)benzoic acid 97%
1g
$ 61.90

Matrix Scientific
4-(5-Formyl-thiophen-2-yl)-benzoic acid >95%
500mg
$ 80.00

Matrix Scientific
4-(5-Formyl-thiophen-2-yl)-benzoic acid >95%
1g
$ 108.00

Matrix Scientific
4-(5-Formyl-thiophen-2-yl)-benzoic acid >95%
5g
$ 429.00

Crysdot
4-(5-Formyl-thiophen-2-yl)-benzoicacid 95+%
10g
$ 324.00

CHESS?
AD024761:4-(5-Formyl-thiophen-2-yl)-benzoicacid 97
5 g
$ 276.00

Chemenu
4-(5-Formyl-thiophen-2-yl)-benzoicacid 95%
10g
$ 306.00

Arctom
4-(5-Formyl-thiophen-2-yl)-benzoicacid ≥95%
5g
$ 258.00

Total 10 raw suppliers

Chemical Property of 4-(5-formylthiophen-2-yl)benzoic Acid

Chemical Property:

Melting Point:284-290 °C
PSA：82.61000
LogP:2.92580
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:232.01941529
Heavy Atom Count:16
Complexity:271

Purity/Quality:

97% ^*data from raw suppliers

4-(5-Formyl-2-thienyl)benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC=C(S2)C=O)C(=O)O
Uses 4-(5-Formyl-2-thienyl)benzoic Acid is a useful intermediate in organic synthesis.

Technology Process of 4-(5-formylthiophen-2-yl)benzoic Acid

There total 4 articles about 4-(5-formylthiophen-2-yl)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 639816-37-8
4-(5-formyl-2-thiophenyl)benzoic acid methyl ester

: 174623-07-5
5-(p-Carboxyphenyl)-2-thiophenealdehyde

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 8h;

Reference yield: 17.0%

: 98-03-3
thiophene-2-carbaldehyde

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 174623-07-5
5-(p-Carboxyphenyl)-2-thiophenealdehyde

Guidance literature:: 4-amino-benzoic acid; With hydrogenchloride; sodium nitrite; In water; at 5 ℃; for 0.333333h;

thiophene-2-carbaldehyde; In water; acetone; at 20 ℃; for 48h;
DOI:10.3390/80300342

Reference yield:

: 4701-17-1
5-bromo-2-thiophencarboxaldehyde

: 174623-07-5
5-(p-Carboxyphenyl)-2-thiophenealdehyde

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; toluene; ethanol / 18 h / 110 °C / Inert atmosphere

2: lithium hydroxide; water / tetrahydrofuran / 8 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; water; sodium carbonate; lithium hydroxide; In tetrahydrofuran; ethanol; water; toluene;