ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester

Base Information

Chemical Name:ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester
CAS No.:174726-87-5
Molecular Formula:C14H10ClN3O3S
Molecular Weight:335.771
Hs Code.:
Mol file:174726-87-5.mol

ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester

Synonyms:ethyl-7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate;7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester;

Suppliers and Price of ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

ChemScene
1,8-Naphthyridine-3-carboxylicacid,7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-,ethylester 99.84%
1g
$ 1200.00

Total 11 raw suppliers

Chemical Property of ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester

Chemical Property:

Boiling Point:518.2±60.0 °C(Predicted)
PKA:1.04±0.10(Predicted)
PSA：102.32000
Density:1.517±0.06 g/cm3(Predicted)
LogP:2.67230

Purity/Quality:

97% ^*data from raw suppliers

1,8-Naphthyridine-3-carboxylicacid,7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-,ethylester 99.84% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester

There total 9 articles about ethyl 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylate, 7-chloro-1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 174726-89-7
ethyl 2-(2,6-dichloro-3-nicotinoyl)-3-(2-thiazolylamino)acrylate

: 174726-87-5
ethyl 7-chloro-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Guidance literature:: With potassium carbonate; In 1,4-dioxane; at 60 ℃; for 1h;
DOI:10.1021/jm0304966

Reference yield:

: 96-50-4
2-thiazolylamine

: 157373-27-8
ethyl 2-[(2,6-dichloropyridin-3-yl)carbonyl]-3-ethoxyacrylate

: 174726-87-5
ethyl 7-chloro-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Guidance literature:: 2-thiazolylamine; ethyl 2-[(2,6-dichloropyridin-3-yl)carbonyl]-3-ethoxyacrylate; In tetrahydrofuran; for 2h; Industry scale;

With potassium carbonate; In tetrahydrofuran; for 6h; Industry scale;