Technology Process of Nirtetralin
There total 7 articles about Nirtetralin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
2: Pd-C
3: 2.) calcium borohydride
4: 1.) lithium di-isopropylamide
5: trifluoroacetic acid
6: lithium aluminium hydride
7: dimethylsulfoxide
With
lithium aluminium tetrahydride; calcium borohydride; trifluoroacetic acid; lithium diisopropyl amide;
palladium on activated charcoal;
In
dimethyl sulfoxide;
DOI:10.1016/0040-4039(81)80108-6
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Pd-C
2: 2.) calcium borohydride
3: 1.) lithium di-isopropylamide
4: trifluoroacetic acid
5: lithium aluminium hydride
6: dimethylsulfoxide
With
lithium aluminium tetrahydride; calcium borohydride; trifluoroacetic acid; lithium diisopropyl amide;
palladium on activated charcoal;
In
dimethyl sulfoxide;
DOI:10.1016/0040-4039(81)80108-6
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 320 mg / TFA / CH2Cl2 / 3 h / Ambient temperature
2: LiAlH4 / tetrahydrofuran / 3 h / Ambient temperature
3: 129 mg / NaH / dimethylsulfoxide / 2.5 h / Ambient temperature
With
lithium aluminium tetrahydride; sodium hydride; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
