2-Benzoylcyclododecan-1-one

Base Information

Chemical Name:2-Benzoylcyclododecan-1-one
CAS No.:17874-84-9
Molecular Formula:C19H26O2
Molecular Weight:286.414
Hs Code.:
European Community (EC) Number:661-041-3
DSSTox Substance ID:DTXSID90399435

Synonyms:2-benzoylcyclododecan-1-one;17874-84-9;2-BENZOYL-1-CYCLODODECANONE;DTXSID90399435;AKOS024339750

Suppliers and Price of 2-Benzoylcyclododecan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Benzoylcyclododecan-1-one

Chemical Property:

XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:286.193280068
Heavy Atom Count:21
Complexity:329

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCCCCC(=O)C(CCCC1)C(=O)C2=CC=CC=C2

Technology Process of 2-Benzoylcyclododecan-1-one

There total 4 articles about 2-Benzoylcyclododecan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 98-88-4
benzoyl chloride

: 830-13-7
cyclododecanone

: 17874-84-9
2-benzoylcyclododecanone

Guidance literature:: cyclododecanone; With triethyl gallium; In hexane; chlorobenzene; at 125 ℃; for 2h;

benzoyl chloride; In hexane; chlorobenzene; at 20 ℃; for 0.166667h;
DOI:10.1021/ol061948m

Reference yield: 49.0%

: 55314-44-8,55314-46-0,51584-36-2
[(cyclododec-1-en-1-yl)oxy](trimethyl)silane

: 98-88-4
benzoyl chloride

: 17874-84-9
2-benzoylcyclododecanone

Guidance literature:: benzoyl chloride; With titanium tetrachloride; In dichloromethane; at -80 ℃; Inert atmosphere;

[(cyclododec-1-en-1-yl)oxy](trimethyl)silane; In dichloromethane; at -80 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/hlca.201100375

Reference yield:

: 830-13-7
cyclododecanone

: 17874-84-9
2-benzoylcyclododecanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: titanium tetrachloride / dichloromethane / -80 °C / Inert atmosphere

2.2: 2 h / -80 - 20 °C / Inert atmosphere

With titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; 2.1: Mukaiyama reaction / 2.2: Mukaiyama reaction;
DOI:10.1002/hlca.201100375