2,8-Diazaspiro[5.5]undecane

Base Information

• Chemical Name: 2,8-Diazaspiro[5.5]undecane
• CAS No.: 180-50-7
• Molecular Formula: C9H18N2
• Molecular Weight: 154.255
• Hs Code.: 2933990090
• European Community (EC) Number: 847-782-7
• DSSTox Substance ID: DTXSID40576072
• Nikkaji Number: J3.230.182G,J79.470H
• Wikidata: Q82465598
• Mol file: 180-50-7.mol

Synonyms:2,8-Diazaspiro[5.5]undecane;180-50-7;2,8-Diazaspiro[5,5]undecane;MFCD11043254;SCHEMBL165883;DTXSID40576072;AKOS006281701;SB41817;SY193010;EN300-90607;G23700

Chemical Property of 2,8-Diazaspiro[5.5]undecane

Chemical Property:

• Vapor Pressure: 0.067mmHg at 25°C
• Boiling Point: 230.252oC at 760 mmHg
• Flash Point: 107.015oC
• PSA: 24.06000
• Density: 0.989g/cm3
• LogP: 1.39720
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 154.146998583
• Heavy Atom Count: 11
• Complexity: 118

Purity/Quality:

97% ^*data from raw suppliers

2,8-Diazaspiro[5.5]undecane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2(CCCNC2)CNC1

Technology Process of 2,8-Diazaspiro[5.5]undecane

There total 5 articles about 2,8-Diazaspiro[5.5]undecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,8-bis(diphenylmethyl)-2,8-diazaspiro<5.5>undecane dihydrochloride (128243-96-9) → 2,8-diazaspiro[5.5]undecane (180-50-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00170a035

Reference yield:

→ 2,8-diazaspiro[5.5]undecane (180-50-7)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1002/hlca.19530360719

Reference yield:

→ 2,8-diazaspiro[5.5]undecane (180-50-7)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1002/hlca.19530360719

upstream raw materials:

2,8-bis(diphenylmethyl)-2,8-diazaspiro<5.5>undecane dihydrochloride

Downstream raw materials:

2,8-diazaspiro[5.5]undecane-2-carboxylic acid tert-butyl ester