Lenthionine

Base Information

• Chemical Name: Lenthionine
• CAS No.: 292-46-6
• Molecular Formula: C2H4 S5
• Molecular Weight: 188.384
• Hs Code.: 2932999099
• NSC Number: 291119
• UNII: 71G9U1CIRD
• DSSTox Substance ID: DTXSID20183460
• Nikkaji Number: J5.458E
• Wikipedia: Lenthionine
• Wikidata: Q3181449
• Metabolomics Workbench ID: 44787
• ChEMBL ID: CHEMBL4288485
• Mol file: 292-46-6.mol

Synonyms:1,2,3,5,6-pentathiepane;lenthionine

Chemical Property of Lenthionine

Chemical Property:

• Vapor Pressure: 8.28E-05mmHg at 25°C
• Melting Point: 60-61°
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 351.5 °C at 760 mmHg
• Flash Point: 190.3 °C
• PSA: 126.50000
• Density: 1.549 g/cm³
• LogP: 3.32600
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 187.89165600
• Heavy Atom Count: 7
• Complexity: 39.3

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,5,6-Pentathiepane 90% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1SSCSSS1

Technology Process of Lenthionine

There total 8 articles about Lenthionine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

bis-chloromethyl disulfide (18994-69-9) → 1,2,3,5,6-pentathiepane (292-46-6)

Guidance literature:

With disodium tetrasulfide; adogen 464; In water; benzene; for 3h;

DOI:10.1016/S0040-4039(01)92873-4

Reference yield: 30.0%

1,2,4,5-tetrathiane (291-22-5) → 1,2,3,5,6-pentathiepane (292-46-6)

Guidance literature:

With disodium tetrasulfide; In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1246/cl.1988.1517

Reference yield: 28.0%

carbon disulfide (75-15-0,12122-00-8) + 1,1-dibromomethane (74-95-3) → 1,2,3,5,6-pentathiepane (292-46-6)

Guidance literature:

carbon disulfide; With sodium sulfide; tetrabutylammomium bromide; In water; toluene; at 20 ℃; for 1h;

With sulfur; In water; toluene; at 20 ℃; for 1h;

1,1-dibromomethane; In water; toluene; at 20 ℃; Reagent/catalyst; Solvent; Temperature; Time;

upstream raw materials:

1,2,4,5-tetrathiane

diiodomethane

sodium tetrathiopercarbonate

bis-chloromethyl disulfide

Refernces

• 1、 -. "PRODUCTION METHOD FOR 1,2,3,5,6-PENTATHIEPANE". Paragraph 0053; 0054; 0055. . Retrieved 2021/01/25.
• 2、 -. "METHOD FOR PRODUCING 1,2,3,5,6-PENTATHIEPANE". Paragraph 0026; 0027; 0028; 0029; 0030. . Retrieved 2018/09/25.