5-Naphthalen-1-yloxolan-2-one

Base Information

Chemical Name:5-Naphthalen-1-yloxolan-2-one
CAS No.:180987-85-3
Molecular Formula:C14H12O2
Molecular Weight:212.24400
Hs Code.:
DSSTox Substance ID:DTXSID70383175
Nikkaji Number:J746.384G
Mol file:180987-85-3.mol

Synonyms:5-naphthalen-1-yloxolan-2-one;180987-85-3;DIHYDRO-5-(1-NAPHTHALENYL)-;Dihydro-5-(1-naphthalenyl)-2-furanone;SCHEMBL576000;DTXSID70383175;FT-0667029;5-(1-Naphthyl)-4,5-dihydrofuran-2(3H)-one

Suppliers and Price of 5-Naphthalen-1-yloxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dihydro-5-(1-naphthalenyl)-2-furanone
25mg
$ 165.00

Total 2 raw suppliers

Chemical Property of 5-Naphthalen-1-yloxolan-2-one

Chemical Property:

PSA：26.30000
LogP:3.21790
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:212.083729621
Heavy Atom Count:16
Complexity:274

Purity/Quality:

97% ^*data from raw suppliers

Dihydro-5-(1-naphthalenyl)-2-furanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)OC1C2=CC=CC3=CC=CC=C32
Uses Dihydro-5-(1-naphthalenyl)-2-furanone (cas# 180987-85-3) is a compound useful in organic synthesis.

Technology Process of 5-Naphthalen-1-yloxolan-2-one

There total 3 articles about 5-Naphthalen-1-yloxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 4653-13-8
4-(1-naphthyl)-4-oxobutanoic acid

: 180987-85-3
5-naphthalen-1-yldihydrofuran-2-one

Guidance literature:: With gallium(III) trichloride; phenylsilane; In benzene; at 60 ℃; for 24h;
DOI:10.1039/c6ra19286f

Reference yield: 61.0%

: 115413-93-9,133690-97-8
1-(naphthalen-1-yl)but-3-yn-1-ol

: 180987-85-3
5-naphthalen-1-yldihydrofuran-2-one

Guidance literature:: 1-(naphthalen-1-yl)but-3-yn-1-ol; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 1h;

With Trimethyl borate; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; at 0 - 20 ℃; for 1h;
DOI:10.1021/acs.orglett.1c00840

Reference yield:

: 66-77-3
1-naphthaldehyde

: 180987-85-3
5-naphthalen-1-yldihydrofuran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: zinc / tetrahydrofuran / 1 h / 0 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C

2.2: 2 h / 0 - 20 °C

2.3: 1 h / 0 - 20 °C

With lithium hexamethyldisilazane; zinc; In tetrahydrofuran;
DOI:10.1021/acs.orglett.1c00840