Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate

Base Information

Chemical Name:Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate
CAS No.:181478-27-3
Molecular Formula:C₁₅H₁₅NO₃S
Molecular Weight:289.355
Hs Code.:
DSSTox Substance ID:DTXSID20570593
Wikidata:Q82458098
Mol file:181478-27-3.mol

Synonyms:Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate;181478-27-3;DTXSID20570593

Suppliers and Price of Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:289.07726451
Heavy Atom Count:20
Complexity:355

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C=C(S1)C2=CC=CC=C2)NC(=O)C

Technology Process of Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate

There total 1 articles about Ethyl 3-acetamido-5-phenylthiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 108-24-7
acetic anhydride

: 88534-50-3
ethyl 3-amino-5-(phenyl)thiophene-2-carboxylate

: 181478-27-3
3-acetamido-2-carbethoxy-5-phenylthiophene

Guidance literature:: With zinc; for 0.166667h;

Reference yield: 68.0%

: 181478-27-3
3-acetamido-2-carbethoxy-5-phenylthiophene

: 181478-28-4
2-methyl-3-N-amino-6-phenylthienoyl<3,2-d>pyrimidin-4(3H)-one

Guidance literature:: With hydrazine hydrate; In ethanol; for 1h; Heating;

Reference yield:

: 181478-27-3
3-acetamido-2-carbethoxy-5-phenylthiophene

: 1-(2-methoxy-phenyl)-3-(2-methyl-4-oxo-6-phenyl-4H-thieno[3,2-d]pyrimidin-3-yl)-thiourea

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / hydrazine hydrate / ethanol / 1 h / Heating

2: ethanol / 6 h / Heating

With hydrazine hydrate; In ethanol;