2-(Allyloxy)benzohydrazide

Base Information

• Chemical Name: 2-(Allyloxy)benzohydrazide
• CAS No.: 18167-41-4
• Molecular Formula: C10H12N2O2
• Molecular Weight: 192.21400
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID20406520
• Nikkaji Number: J1.738.423F
• Wikidata: Q82211516
• Mol file: 18167-41-4.mol

Synonyms:2-(ALLYLOXY)BENZOHYDRAZIDE;18167-41-4;2-prop-2-enoxybenzohydrazide;2-(prop-2-en-1-yloxy)benzohydrazide;DTXSID20406520;AKOS000319440;SB86430;VS-06863;CS-0324123

Chemical Property of 2-(Allyloxy)benzohydrazide

Chemical Property:

• PSA: 64.35000
• LogP: 1.94610
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 192.089877630
• Heavy Atom Count: 14
• Complexity: 206

Purity/Quality:

98%Min ^*data from raw suppliers

2-(allyloxy)benzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CCOC1=CC=CC=C1C(=O)NN

Technology Process of 2-(Allyloxy)benzohydrazide

There total 9 articles about 2-(Allyloxy)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methyl 2-allyloxybenzoate (6282-42-4) → 2-allyloxybenzhydrazide (18167-41-4)

Guidance literature:

With hydrazine hydrate; for 6h; Heating;

DOI:10.1246/bcsj.53.429

Reference yield: 60.0%

2--1-(p-tolylsulfonyl)hydrazine (74618-09-0) → 2-allyloxybenzhydrazide (18167-41-4)

Guidance literature:

With potassium hydroxide; In ethanol; for 1h; Heating;

DOI:10.1246/bcsj.53.429

Reference yield:

2-allyloxybenzoic acid (59086-52-1) → 2-allyloxybenzhydrazide (18167-41-4)

Guidance literature:

Multi-step reaction with 2 steps

1: EDCI / CH₂Cl₂ / 20 °C

2: 1.181 g / TFA / 1 h / 0 °C

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane;

DOI:10.1016/S0040-4020(02)00490-8

upstream raw materials:

methyl 2-allyloxybenzoate

2--1-(p-tolylsulfonyl)hydrazine

2-allyloxybenzoic acid

2-allyloxybenzoyl chloride