2-(2,4,5-Trichlorophenoxy)acetamide

Base Information

• Chemical Name: 2-(2,4,5-Trichlorophenoxy)acetamide
• CAS No.: 18288-24-9
• Molecular Formula: C8H6Cl3NO2
• Molecular Weight: 254.5
• DSSTox Substance ID: DTXSID601294161
• Nikkaji Number: J1.323.983E
• Mol file: 18288-24-9.mol

Synonyms:2-(2,4,5-trichlorophenoxy)acetamide;SCHEMBL5533199;DTXSID601294161;STK208207;AKOS001266180;SR-01000199350;SR-01000199350-1;18288-24-9

Chemical Property of 2-(2,4,5-Trichlorophenoxy)acetamide

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 252.946412
• Heavy Atom Count: 14
• Complexity: 215

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC(=O)N

Technology Process of 2-(2,4,5-Trichlorophenoxy)acetamide

There total 4 articles about 2-(2,4,5-Trichlorophenoxy)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2,4,5-trichlorophenoxy)acetyl chloride (777-08-2) → (2,4,5-trichloro-phenoxy)-acetic acid amide (18288-24-9)

Guidance literature:

With ammonium hydroxide;

DOI:10.1021/ja01169a065

Reference yield:

2,4,5-Trichlorophenoxyacetic acid (93-76-5) → (2,4,5-trichloro-phenoxy)-acetic acid amide (18288-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / anschliessendes Kochen

2: concentrated aqueous NH₃

With ammonium hydroxide; thionyl chloride;

DOI:10.1021/ja01169a065

Reference yield:

2,4,5-trichlorophenol (95-95-4) + Chloroacetamide (79-07-2) → (2,4,5-trichloro-phenoxy)-acetic acid amide (18288-24-9)

Guidance literature:

With sodium hydroxide; isopropyl alcohol;

upstream raw materials:

2-(2,4,5-trichlorophenoxy)acetyl chloride

2,4,5-trichlorophenol

Chloroacetamide

2,4,5-Trichlorophenoxyacetic acid

Downstream raw materials:

2,4-5-Trichlorphenoxy-acetylisocyanat

N-((3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1H-pyrazol-5-yl)carbamoyl)-2-(2,4,5-trichlorophenoxy) acetamide

2,4,5-Trichlorophenoxyacetic acid