5-Acetyl-5,10-dihydrophenazine

Base Information

• Chemical Name: 5-Acetyl-5,10-dihydrophenazine
• CAS No.: 18345-95-4
• Molecular Formula: C14H12N2O
• Molecular Weight: 224.262
• DSSTox Substance ID: DTXSID80352236
• Nikkaji Number: J813.919I
• Wikidata: Q82129268
• ChEMBL ID: CHEMBL1570626
• Mol file: 18345-95-4.mol

Synonyms:5-acetyl-5,10-dihydrophenazine;18345-95-4;1-(10H-phenazin-5-yl)ethanone;1-(Phenazin-5(10H)-yl)ethanone;1-(Phenazin-5(10H)-yl)ethan-1-one;ZINC00123843;CBMicro_008987;Oprea1_595066;MLS000700656;SCHEMBL7686595;CHEMBL1570626;DTXSID80352236;HMS2559E07;SMSF0003707;MFCD00546569;AKOS002346531;SMR000225268;SY265591;BIM-0009129.P001;CS-0448516;EN300-18560588;SR-01000196737;1-(5,10-DIHYDROPHENAZIN-5-YL)ETHAN-1-ONE;SR-01000196737-1

Chemical Property of 5-Acetyl-5,10-dihydrophenazine

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 224.094963011
• Heavy Atom Count: 17
• Complexity: 283

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)N1C2=CC=CC=C2NC3=CC=CC=C31

Technology Process of 5-Acetyl-5,10-dihydrophenazine

There total 8 articles about 5-Acetyl-5,10-dihydrophenazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

Phenazin (92-82-0) + acetaldehyde (75-07-0,9002-91-9) → 5-acetyl-5,10-dihydrophenazine (18345-95-4)

Guidance literature:

at 10 ℃; for 6h; Irradiation;

DOI:10.1246/bcsj.53.1777

Reference yield:

5,10-dihydrophenazine (613-32-1) + acetic anhydride (108-24-7) → 5-acetyl-5,10-dihydrophenazine (18345-95-4) + 1,1′-(phenazin-5,10-diyl)diethanone (7478-17-3)

Guidance literature:

at 135 ℃; for 0.166667h; Overall yield = 75 %; Overall yield = 600 mg;

Reference yield:

Phenazin (92-82-0) → 5-acetyl-5,10-dihydrophenazine (18345-95-4) + 1,1′-(phenazin-5,10-diyl)diethanone (7478-17-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydrogen sulfate / water; ethanol / Reflux

2: 0.17 h / 135 °C

With sodium hydrogen sulfate; In ethanol; water;

upstream raw materials:

Phenazin

acetic anhydride

5,10-dihydrophenazine

acetaldehyde

Downstream raw materials:

2-(10-Acetyl-5,10-dihydro-5-phenazinyl)benzoesaeure-methylester

Phenazin

5-Ethyl-9,9-dimethyl-5H,9H-chino<3,2,1-de>phenazin

2-(10-Ethyl-5,10-dihydro-5-phenazinyl)-α,α-dimethylbenzolmethanol