2'-Acetyltaxol

Base Information

Chemical Name:2'-Acetyltaxol
CAS No.:92950-40-8
Molecular Formula:C49H53 N O15
Molecular Weight:895.958
Hs Code.:
DSSTox Substance ID:DTXSID001317325
Nikkaji Number:J736.132G
ChEMBL ID:CHEMBL302351
Mol file:92950-40-8.mol

Synonyms:2'-acetyltaxol;taxol 2'-acetate

Suppliers and Price of 2'-Acetyltaxol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2''-Acetyltaxol
50mg
$ 235.00

American Custom Chemicals Corporation
2'-ACETYLTAXOL 95.00%
5MG
$ 502.04

Total 24 raw suppliers

Chemical Property of 2'-Acetyltaxol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:956.3°Cat760mmHg
Flash Point:532.1°C
PSA：227.36000
Density:1.38g/cm³
LogP:4.69740
XLogP3:3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:16
Exact Mass:895.34151998
Heavy Atom Count:65
Complexity:1910

Purity/Quality:

98%Min ^*data from raw suppliers

2''-Acetyltaxol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)OC(=O)C)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Isomeric SMILES:CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)OC(=O)C)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Uses 2''-Acetyltaxol is a microtubule polymerization-inactive taxol analog.

Technology Process of 2'-Acetyltaxol

There total 5 articles about 2'-Acetyltaxol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-24-7
acetic anhydride

: 90332-63-1
7-O-(β-xylosyl)-10-deacetyltaxol

: 33069-62-4
taxol

: 92950-40-8
2'-O-acetyl-paclitaxel

Guidance literature:: 7-O-(β-xylosyl)-10-deacetyltaxol; With sodium periodate; sulfuric acid; In methanol; chloroform; water; at 20 ℃; for 3h;

acetic anhydride; With pyridine; at 100 ℃; for 0.5h;

With acetic acid; phenylhydrazine; In methanol; at 50 - 60 ℃; for 3h;

Reference yield:

: 108-24-7
acetic anhydride

: 78432-77-6
10-deacetylpaclitaxel

: 92950-40-8
2'-O-acetyl-paclitaxel

Guidance literature:: 10-deacetylpaclitaxel; With cerium(III) chloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

acetic anhydride; In tetrahydrofuran; at 20 ℃; for 2h; Product distribution / selectivity;