demeclocycline

Base Information

Chemical Name:demeclocycline
CAS No.:127-33-3
Molecular Formula:C21H21 Cl N2 O8
Molecular Weight:464.859
Hs Code.:
Mol file:127-33-3.mol

Synonyms:2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-(8CI); 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,[4S-(4a,4aa,5aa,6b,12aa)]-; 6-Demethyl-7-chlorotetracycline;6-Demethyl-7-chlortetracycline; 6-Demethylchlorotetracycline;6-Demethylchlortetracycline;7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide;7-Chloro-6-demethyltetracycline; Bioterciclin; Chlortetracycline, 6-demethyl-;DMCT; DMCT (antibiotic); Deganol; Demeclocycline; Demeclor;Demethylchlorotetracycline; Demethylchlortetracyclin;Demethylchlortetracycline; Demetraclin; Diuciclin; Elkamicina; Ledermycin;Mexocine; Novotriclina; Perciclina; Periciclina; RP 10192; Sumaclina;Tri-demethylchlortetracycline

Suppliers and Price of demeclocycline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 28 raw suppliers

Chemical Property of demeclocycline

Chemical Property:

Vapor Pressure:1.02E-26mmHg at 25°C
Melting Point:176°C (rough estimate)
Refractive Index:1.6000 (estimate)
Boiling Point:684.5°Cat760mmHg
PKA:4.50±1.00(Predicted)
Flash Point:367.8°C
PSA：181.62000
Density:1.75g/cm³
LogP:0.96520
Water Solubility.:1.4g/L(25 oC)

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Uses Demeclocycline, a chlortetracycline analogue produced by a mutagenised strain of Streptomyces aureofaciens, was first isolated in 1957. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Demeclocycline has been extensively cited in the literature with over 800 references relating almost exclusively to in vivo use.
Therapeutic Function Antibacterial

Technology Process of demeclocycline

There total 1 articles about demeclocycline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127-33-3
Demeclocycline

Guidance literature:: von Cu-Chelat;
DOI:10.1002/jps.2600540707

Reference yield: 92.0%

: 127-33-3
Demeclocycline

: 987-02-0
6-demethyltetracycline

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; urea; In water; at 25 - 45 ℃; for 4.16667h; under 3000.3 - 4500.45 Torr; Temperature; Pressure; Reagent/catalyst;

Reference yield: 88.0%

: 127-33-3
Demeclocycline

: 808-26-4,2696-12-0,15964-02-0,39105-46-9
sancycline

Guidance literature:: With 10% rhodium on carbon; hydrogen; toluene-4-sulfonic acid; In methanol; at 20 ℃; for 15h; under 11251.1 - 18751.9 Torr; Reagent/catalyst; Pressure; Solvent; Autoclave;