5-[5-Hydroxy-2-(methoxycarbonyl)-3-pentylphenoxy]-4-methoxy-6-pentylsalicylic acid

Base Information

Chemical Name:5-[5-Hydroxy-2-(methoxycarbonyl)-3-pentylphenoxy]-4-methoxy-6-pentylsalicylic acid
CAS No.:101910-69-4
Molecular Formula:C26H34 O8
Molecular Weight:474.5434
Hs Code.:
Mol file:101910-69-4.mol

Synonyms:Epiforellic1 acid; Epiphorellic acid 1

Suppliers and Price of 5-[5-Hydroxy-2-(methoxycarbonyl)-3-pentylphenoxy]-4-methoxy-6-pentylsalicylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-[5-Hydroxy-2-(methoxycarbonyl)-3-pentylphenoxy]-4-methoxy-6-pentylsalicylic acid

Chemical Property:

Vapor Pressure:1.84E-16mmHg at 25°C
Boiling Point:624.5°Cat760mmHg
PKA:3.02±0.40(Predicted)
Flash Point:203.4°C
PSA：122.52000
Density:1.198g/cm³
LogP:5.84890

Purity/Quality:: 96% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-[5-Hydroxy-2-(methoxycarbonyl)-3-pentylphenoxy]-4-methoxy-6-pentylsalicylic acid

There total 12 articles about 5-[5-Hydroxy-2-(methoxycarbonyl)-3-pentylphenoxy]-4-methoxy-6-pentylsalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 124281-34-1
benzyl 3-(5'-benzyloxy-2'-methoxycarbonyl-3'-pentylphenoxy)-6-hydroxy-4-methoxy-2-pentylbenzoate

: 101910-69-4
6-hydroxy-3-(5'-hydroxy-2'-methoxycarbonyl-3'-pentylphenoxy)-4-methoxy-2-pentylbenzoic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 15h;

Reference yield:

: 53530-17-9
ethyl 2,4-dimethoxy-6-pentylbenzoate

: 101910-69-4
6-hydroxy-3-(5'-hydroxy-2'-methoxycarbonyl-3'-pentylphenoxy)-4-methoxy-2-pentylbenzoic acid

Guidance literature:: Multi-step reaction with 12 steps

1: 84 percent / SnCl₄ / CH₂Cl₂ / 2 h / Ambient temperature

2: 92 percent / BCl₃ / CH₂Cl₂ / 0.5 h / -78 °C

3: 53 percent / sodium / 20 h / 120 - 130 °C

4: 82 percent / K₂CO₃ / acetone / 20 h / Heating

5: m-chloroperbenzoic acid / CH₂Cl₂ / 1 h / Ambient temperature

6: 10percent aq. KOH / methanol / 0.75 h / 0 °C

7: H₂ / 10percent Pd/C / ethyl acetate / 16 h

8: diethyl ether / 2 h / Ambient temperature

9: 73 percent / trifluoroacetic anhydride / toluene / 2 h / Ambient temperature

10: 32 percent / K₂CO₃ / dimethylsulfoxide / 22 h / 75 - 76 °C

11: 77 percent / ethyl acetate; diethyl ether / 0.07 h / Ambient temperature

12: 88 percent / H₂ / 10percent Pd/C / ethyl acetate / 15 h

With potassium hydroxide; hydrogen; sodium; boron trichloride; tin(IV) chloride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane; dimethyl sulfoxide; ethyl acetate; acetone; toluene;

Reference yield:

: 124281-30-7
3,6-Dihydroxy-4-methoxy-2-pentyl-benzoic acid

: 101910-69-4
6-hydroxy-3-(5'-hydroxy-2'-methoxycarbonyl-3'-pentylphenoxy)-4-methoxy-2-pentylbenzoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: diethyl ether / 2 h / Ambient temperature

2: 73 percent / trifluoroacetic anhydride / toluene / 2 h / Ambient temperature

3: 32 percent / K₂CO₃ / dimethylsulfoxide / 22 h / 75 - 76 °C

4: 77 percent / ethyl acetate; diethyl ether / 0.07 h / Ambient temperature

5: 88 percent / H₂ / 10percent Pd/C / ethyl acetate / 15 h

With hydrogen; potassium carbonate; trifluoroacetic anhydride; palladium on activated charcoal; In diethyl ether; dimethyl sulfoxide; ethyl acetate; toluene;