1,4-Bis((prop-2-yn-1-yloxy)methyl)benzene

Base Information

• Chemical Name: 1,4-Bis((prop-2-yn-1-yloxy)methyl)benzene
• CAS No.: 18473-19-3
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• European Community (EC) Number: 894-935-9
• Mol file: 18473-19-3.mol

Synonyms:1,4-Bis((prop-2-yn-1-yloxy)methyl)benzene;18473-19-3;1,4-bis[(prop-2-yn-1-yloxy)methyl]benzene;SCHEMBL3423851;CS-0170464;G68663

Chemical Property of 1,4-Bis((prop-2-yn-1-yloxy)methyl)benzene

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 214.099379685
• Heavy Atom Count: 16
• Complexity: 240

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C#CCOCC1=CC=C(C=C1)COCC#C

Technology Process of 1,4-Bis((prop-2-yn-1-yloxy)methyl)benzene

There total 2 articles about 1,4-Bis((prop-2-yn-1-yloxy)methyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

propargyl alcohol (107-19-7) + p-Xylylene dichloride (623-25-6) → 1,4-bis(prop-2-ynyloxymethyl)benzene (18473-19-3)

Guidance literature:

With sodium hydroxide; tetrabutylammomium bromide;

Reference yield: 34.0%

p-xylylene glycol (589-29-7) + propargyl bromide (106-96-7) → (4-((prop-2-yn-1-yloxy)methyl)phenyl)methanol + 1,4-bis(prop-2-ynyloxymethyl)benzene (18473-19-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran; toluene; for 15h;

DOI:10.1002/anie.200700408

Reference yield: 58.0%

1,4-bis(prop-2-ynyloxymethyl)benzene (18473-19-3) → 1,4-Bis(allenyloxy)xylylene (134621-79-7)

Guidance literature:

With potassium tert-butylate;

upstream raw materials:

propargyl alcohol

p-Xylylene dichloride

p-xylylene glycol

propargyl bromide

Downstream raw materials:

1,4-Bis(allenyloxy)xylylene

C₇₄H₇₂N₁₀O₁₆