8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene

Base Information

Chemical Name:8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene
CAS No.:185099-65-4
Molecular Formula:C15H19N
Molecular Weight:213.323
Hs Code.:
DSSTox Substance ID:DTXSID90708003
Mol file:185099-65-4.mol

Synonyms:185099-65-4;SCHEMBL8200389;DTXSID90708003;8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene

Suppliers and Price of 8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:213.151749610
Heavy Atom Count:16
Complexity:294

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=CC3CCC(C2)N3C

Technology Process of 8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene

There total 2 articles about 8-Methyl-3-(2-methylphenyl)-8-azabicyclo[3.2.1]oct-2-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 932-31-0
ortho-tolylmagnesium bromide

: 893429-75-9,893429-77-1,183810-37-9
8-Methyl-3-trifluoromethanesulfonyl-oxy-8-azabicyclo[3.2.1]oct-2-ene

: 185099-65-4
8-methyl-3-o-tolyl-8-aza-bicyclo[3.2.1]oct-2-ene

Guidance literature:: With copper(l) iodide; In tetrahydrofuran; at 0 ℃;
DOI:10.1016/S0960-894X(03)00261-0

Reference yield:

: 532-24-1
tropinone

: 185099-65-4
8-methyl-3-o-tolyl-8-aza-bicyclo[3.2.1]oct-2-ene

Guidance literature:: Multi-step reaction with 2 steps

1.1: KN(TMS)2 / tetrahydrofuran / -78 °C

1.2: 75 percent / tetrahydrofuran / -78 °C

2.1: 94 percent / CuI / tetrahydrofuran / 0 °C

With copper(l) iodide; potassium hexamethylsilazane; In tetrahydrofuran;
DOI:10.1016/S0960-894X(03)00261-0