Methyl-1-testosterone

Base Information

Chemical Name:Methyl-1-testosterone
CAS No.:65-04-3
Molecular Formula:C₂₀H₃₀O₂
Molecular Weight:302.457
Hs Code.:
European Community (EC) Number:691-758-7
UNII:21O907N0NH
DSSTox Substance ID:DTXSID20879831
Nikkaji Number:J2.069.330D
Wikipedia:Methyl-1-testosterone
Wikidata:Q6823920
Metabolomics Workbench ID:146220
Mol file:65-04-3.mol

Synonyms:Methyl-1-testosterone;65-04-3;(+)-Methyl-1-testosterone;UNII-21O907N0NH;SC-11195;21O907N0NH;17alpha-Methyl-17beta-hydroxy-5alpha-androst-1-en-3-one;17beta-Hydroxy-17alpha-methyl-5alpha-androst-1-ene-3-one;17alpha-Methyl-17beta-hydroxy-delta1-5alpha-androsten-3-one;Oxandrolone impurity, delta1-mestalone- [USP];Androst-1-en-3-one, 17-hydroxy-17-methyl-, (5alpha,17beta)-;(5S,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-5,6,7,8,9,11,12,14,15,16-decahydro-4H-cyclopenta[a]phenanthren-3-one;17beta-hydroxy-17alpha-methyl-5alpha-androst-1-en-3-one;17alpha-Methyl-1-testosterone;17.beta.-hydroxy-17.alpha.-methyl-5.alpha.-androst-1-en-3-one;SCHEMBL4115261;DTXSID20879831;JRNSSSJKIGAFCT-YDSAWKJFSA-N;AKOS015962937;DB01572;17-ALPHA-METHYL-1-TESTOSTERONE;Q6823920;17alpha-Methyl-17-hydroxy-5alpha-androsta-1-ene-3-one;(5alpha,17beta)-17-Hydroxy-17-methylandrost-1-en-3-one;OXANDROLONE IMPURITY, .DELTA.1-MESTALONE- [USP IMPURITY];17.ALPHA.-METHYL-17.BETA.-HYDROXY-5.ALPHA.-ANDROST-1-EN-3-ONE;17.BETA.-HYDROXY-17.ALPHA.-METHYL-5.ALPHA.-ANDROST-1-ENE-3-ONE;17-Methyl-1-Testosterone : (5 a ,17 b )-17-Hydroxy-17-methylandrosta-1-en-3-one;17.ALPHA.-METHYL-17.BETA.-HYDROXY-.DELTA.1-5.ALPHA.-ANDROSTEN-3-ONE;ANDROST-1-EN-3-ONE, 17-HYDROXY-17-METHYL-, (5.ALPHA.,17.BETA.)-;18167-94-7

Suppliers and Price of Methyl-1-testosterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
17α-methyl-1-Testosterone
1mg
$ 125.00

American Custom Chemicals Corporation
17-BETA-HYDROXY-17-ALPHA-METHYL-5-ALPHA-ANDROST-1-ENE-3-ONE 95.00%
5MG
$ 498.44

AK Scientific
Methyl-1-testosterone
1mg
$ 255.00

Total 111 raw suppliers

Chemical Property of Methyl-1-testosterone

Chemical Property:

Appearance/Colour:white solid
Melting Point:154-155 °C
Boiling Point:422.719 °C at 760 mmHg
PKA:15.14±0.60(Predicted)
Flash Point:180.4 °C
PSA：37.30000
Density:1.083 g/cm³
LogP:4.12520
Solubility.:H2O: ≤0.5 mg/mL
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:302.224580195
Heavy Atom Count:22
Complexity:538

Purity/Quality:

99%, ^*data from raw suppliers

17α-methyl-1-Testosterone ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 45-63
Safety Statements: 53-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2(C)O)CCC4C3(C=CC(=O)C4)C
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(C=CC(=O)C4)C
Uses Methyl-1-Testosterone is a derivative of dihydrotestosterone. Methyl-1-Testosterone is a designer anabolic steroid that is on the world anti-doping agency’s (WADA) prohibited list.

Technology Process of Methyl-1-testosterone

There total 11 articles about Methyl-1-testosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 18167-94-7,35937-38-3,132830-76-3,65-04-3
5α-17β-hydroxy-17α-methyl-Δ¹-androsten-3-one

Guidance literature:

Reference yield: 86.0%

: 74252-42-9,76333-34-1
2α-bromo-17β-hydroxy-17α-methyl-5α-androstan-3-one

: 18167-94-7,35937-38-3,132830-76-3,65-04-3
5α-17β-hydroxy-17α-methyl-Δ¹-androsten-3-one

Guidance literature:: With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; [CoCl₂(dmgH)2(pyridine)]; potassium carbonate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 16h; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1021/jacs.1c06768