Technology Process of (Z)-6,10-dimethylundec-3-en-2-one
There total 1 articles about (Z)-6,10-dimethylundec-3-en-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
barium dihydroxide;
In
water;
for 3h;
Heating;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Chiralcel OD-H (4.6 x 250 mm) / isopropyl alcohol; hexane / 23 °C / Resolution of racemate
2: hydrogen; palladium on activated charcoal / ethanol / 2 h / 20 °C
3: sodium hydride / dichloromethane / 10 h / 20 °C
4: diisobutylaluminium hydride / dichloromethane / 1 h / 0 °C
5: manganese(IV) oxide / dichloromethane / 48 h / 20 °C
6: (R)-(-)-2-(tert-butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid salt; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate / chloroform / 2 h / -30 °C
7: diisobutylaluminium hydride / dichloromethane / 1 h / 0 °C
With
manganese(IV) oxide; (R)-(-)-2-(tert-butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid salt; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; palladium on activated charcoal; hydrogen; sodium hydride; diisobutylaluminium hydride;
In
ethanol; hexane; dichloromethane; chloroform; isopropyl alcohol;
3: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1016/j.tetlet.2014.08.085