1,2-Dimethyl-2,3,3a,6a-tetrahydrocyclopenta(b)pyrrole

Base Information

• Chemical Name: 1,2-Dimethyl-2,3,3a,6a-tetrahydrocyclopenta(b)pyrrole
• CAS No.: 74195-76-9
• Molecular Formula: C₉H₁₇N
• Molecular Weight: 139.241
• DSSTox Substance ID: DTXSID60902758
• Nikkaji Number: J78.007C
• Mol file: 74195-76-9.mol

Synonyms:BRN 0001238;74195-76-9;1,2-Dimethyl-2,3,3a,6a-tetrahydrocyclopenta(b)pyrrole;Cyclopenta(b)pyrrole, 2,3,3a,6a-tetrahydro-1,2-dimethyl-;NoName_3312;SCHEMBL812020;DTXSID60902758;LS-58206;Octahydro-1,2-dimethylcyclopenta[b]pyrrole;Cyclopenta[b]pyrrole, octahydro-1,2-dimethyl-

Chemical Property of 1,2-Dimethyl-2,3,3a,6a-tetrahydrocyclopenta(b)pyrrole

Chemical Property:

• Vapor Pressure: 1.52mmHg at 25°C
• Boiling Point: 169.7°Cat760mmHg
• Flash Point: 52.5°C
• PSA: 3.24000
• Density: 0.904g/cm³
• LogP: 1.81700
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 139.136099547
• Heavy Atom Count: 10
• Complexity: 133

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2CCCC2N1C

Technology Process of 1,2-Dimethyl-2,3,3a,6a-tetrahydrocyclopenta(b)pyrrole

There total 4 articles about 1,2-Dimethyl-2,3,3a,6a-tetrahydrocyclopenta(b)pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-2-methyl-(3ar,6ac)-3,3a,4,5,6,6a-hexahydro-cyclopenta[b]pyrrole (92658-01-0,154592-43-5) → (+/-)-1,2c-dimethyl-(3ar,6ac)-octahydro-cyclopenta[b]pyrrole (74195-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; acetic acid / Hydrogenation

2: methanol. KOH-solution

With potassium hydroxide; acetic acid; platinum;

Reference yield:

(+/-)-6ξ-iodo-2-methyl-(3ar,6ac)-3,3a,4,5,6,6a-hexahydro-cyclopenta[b]pyrrole → (+/-)-1,2c-dimethyl-(3ar,6ac)-octahydro-cyclopenta[b]pyrrole (74195-76-9)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; zinc

2: platinum; acetic acid / Hydrogenation

3: methanol. KOH-solution

With potassium hydroxide; acetic acid; platinum; zinc;

Reference yield:

(+/-)-2-methyl-(3ar,6ac)-3,3a,4,5,6,6a-hexahydro-cyclopenta[b]pyrrol-6t-ol (92259-52-4) → (+/-)-1,2c-dimethyl-(3ar,6ac)-octahydro-cyclopenta[b]pyrrole (74195-76-9)

Guidance literature:

Multi-step reaction with 4 steps

1: aqueous hydriodic acid; phosphorus

2: acetic acid; zinc

3: platinum; acetic acid / Hydrogenation

4: methanol. KOH-solution

With phosphorus; potassium hydroxide; hydrogen iodide; acetic acid; platinum; zinc;

upstream raw materials:

(+/-)-2c-methyl-(3ar,6ac)-octahydro-cyclopenta[b]pyrrole

methyl iodide

(+/-)-2-methyl-(3ar,6ac)-3,3a,4,5,6,6a-hexahydro-cyclopenta[b]pyrrole

(+/-)-2-methyl-(3ar,6ac)-3,3a,4,5,6,6a-hexahydro-cyclopenta[b]pyrrol-6t-ol