Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]-

Base Information

Chemical Name:Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]-
CAS No.:185243-98-5
Molecular Formula:C13H13NO3S2
Molecular Weight:295.383
Hs Code.:
DSSTox Substance ID:DTXSID60453593
Nikkaji Number:J781.791F
Mol file:185243-98-5.mol

Synonyms:185243-98-5;Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]-;SCHEMBL21408687;DTXSID60453593;N-[Tosyl(3-thienyl)methyl]formamide

Suppliers and Price of Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]-

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:295.03368562
Heavy Atom Count:19
Complexity:397

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)C(C2=CSC=C2)NC=O

Technology Process of Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]-

There total 2 articles about Formamide, N-[[(4-methylphenyl)sulfonyl]-3-thienylmethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 498-62-4
3-thiophene carboxaldehyde

: 536-57-2
p-toluene sulfinic acid

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 185243-98-5
N-(thiophen-3-yl(tosyl)methyl)formamide

Guidance literature:: With chloro-trimethyl-silane; In toluene; acetonitrile; at 50 ℃; for 5h;
DOI:10.1016/0040-4039(96)01886-2

Reference yield:

: 824-79-3
sodium 4-methylbenzenesulfinate

: 185243-98-5
N-(thiophen-3-yl(tosyl)methyl)formamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / water; tert-butyl methyl ether

2.1: chloro-trimethyl-silane / acetonitrile; toluene / 50 °C

2.2: 50 °C

With hydrogenchloride; chloro-trimethyl-silane; In tert-butyl methyl ether; water; toluene; acetonitrile;
DOI:10.15227/orgsyn.077.0198

Reference yield: 76.0%

: 185243-98-5
N-(thiophen-3-yl(tosyl)methyl)formamide

: 263389-44-2
[(4-methylphenyl)sulfonyl]-3-thienylmethanisocyanide

Guidance literature:: N-(thiophen-3-yl(tosyl)methyl)formamide; With trichlorophosphate; In tetrahydrofuran; at 25 ℃; for 0.0833333h;

With triethylamine; In tetrahydrofuran; at 0 - 10 ℃;
DOI:10.15227/orgsyn.077.0198