4-ACETOXY-2'-CHLOROBENZOPHENONE

Base Information

• Chemical Name: 4-ACETOXY-2'-CHLOROBENZOPHENONE
• CAS No.: 185606-03-5
• Molecular Formula: C15H11ClO3
• Molecular Weight: 274.69900
• Hs Code.: 2915390090
• Mol file: 185606-03-5.mol

Synonyms:4-ACETOXY-2'-CHLOROBENZOPHENONE;

Chemical Property of 4-ACETOXY-2'-CHLOROBENZOPHENONE

Chemical Property:

• Vapor Pressure: 7.53E-07mmHg at 25°C
• Boiling Point: 407.5oC at 760 mmHg
• Flash Point: 165.4oC
• PSA: 43.37000
• Density: 1.265g/cm3
• LogP: 3.49630

Purity/Quality:

99% ^*data from raw suppliers

4-Acetoxy-2'-chlorobenzophenone >90% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ACETOXY-2'-CHLOROBENZOPHENONE

There total 3 articles about 4-ACETOXY-2'-CHLOROBENZOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(4-hydroxyphenyl)-(2-chlorophenyl)-methanone (55270-71-8) + acetic anhydride (108-24-7) → (4-acetyloxyphenyl)-(2-chlorophenyl)-methanone (185606-03-5)

Guidance literature:

DOI:10.1063/1.472681

Reference yield:

ortho-chlorobenzoic acid (118-91-2) → (4-acetyloxyphenyl)-(2-chlorophenyl)-methanone (185606-03-5)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂ / toluene / 4 h / Heating

2: 1.) AlCl₃, 2.) 1N aq. NaOH / 1.) CS₂, reflux, 6 h, 2.) CS₂

3: 80 percent

With sodium hydroxide; aluminium trichloride; thionyl chloride; In toluene;

DOI:10.1063/1.472681

Reference yield:

o-chlorobenzoyl chloride (609-65-4) → (4-acetyloxyphenyl)-(2-chlorophenyl)-methanone (185606-03-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) AlCl₃, 2.) 1N aq. NaOH / 1.) CS₂, reflux, 6 h, 2.) CS₂

2: 80 percent

With sodium hydroxide; aluminium trichloride;

DOI:10.1063/1.472681

upstream raw materials:

(4-hydroxyphenyl)-(2-chlorophenyl)-methanone

acetic anhydride

o-chlorobenzoyl chloride

ortho-chlorobenzoic acid

Refernces