6-(1-Phenylethyl)-2,2'-bipyridine

Base Information

Chemical Name:6-(1-Phenylethyl)-2,2'-bipyridine
CAS No.:185610-09-7
Molecular Formula:C18H16N2
Molecular Weight:260.338
Hs Code.:
DSSTox Substance ID:DTXSID40571148
Nikkaji Number:J1.345.565A

Synonyms:6-(1-Phenylethyl)-2,2'-bipyridine;185610-09-7;DTXSID40571148

Suppliers and Price of 6-(1-Phenylethyl)-2,2'-bipyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-(1-Phenylethyl)-2,2'-bipyridine

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:260.131348519
Heavy Atom Count:20
Complexity:285

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)C2=CC=CC(=N2)C3=CC=CC=N3

Technology Process of 6-(1-Phenylethyl)-2,2'-bipyridine

There total 3 articles about 6-(1-Phenylethyl)-2,2'-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 106851-33-6
(+)-(S)-2-cyano-6-(1-methylbenzyl)pyridine

: 74-86-2,25067-58-7
acetylene

: 185610-09-7
6-(1-methylbenzene)-2-(2'-pyridyl)pyridine

Guidance literature:: With (η5-cyclopentadienyl)-η4-cycloocta-1,5-dienecobalt(I); In toluene; at 100 ℃; for 24h; under 9120 Torr;
DOI:10.1016/S0022-328X(00)99687-6

Reference yield:

: 10495-73-5
2-bromo-6-(pyridin-2-yl)pyridine

: 85459-20-7
(α-methylbenzyl)zinc bromide

: 185610-09-7
6-(1-methylbenzene)-2-(2'-pyridyl)pyridine

Guidance literature:: With palladium bis[bis(diphenylphosphino)ferrocene] dichloride; In tetrahydrofuran; at 50 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.organomet.5b00326

Reference yield:

: 585-71-7,38661-81-3
(1-bromoethyl)benzne

: 185610-09-7
6-(1-methylbenzene)-2-(2'-pyridyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethylene dibromide; lithium chloride / tetrahydrofuran / 0.33 h / 60 °C / Inert atmosphere

1.2: 0.33 h / 60 °C / Inert atmosphere

1.3: 16 h / 50 °C / Inert atmosphere

2.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride / tetrahydrofuran / 3 h / 50 °C / Inert atmosphere

With palladium bis[bis(diphenylphosphino)ferrocene] dichloride; ethylene dibromide; lithium chloride; In tetrahydrofuran; 2.1: |Negishi Coupling;
DOI:10.1021/acs.organomet.5b00326