ethyl 2-acetylhex-4-enoate

Base Information

• Chemical Name: ethyl 2-acetylhex-4-enoate
• CAS No.: 29149-74-4
• Molecular Formula: C10H16 O3
• Molecular Weight: 184.235
• Mol file: 29149-74-4.mol

Synonyms:NSC 167590

Chemical Property of ethyl 2-acetylhex-4-enoate

Chemical Property:

• Vapor Pressure: 0.0533mmHg at 25°C
• Boiling Point: 234.3°Cat760mmHg
• Flash Point: 93.7°C
• Density: 0.978g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-acetylhex-4-enoate

There total 6 articles about ethyl 2-acetylhex-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E/Z)-crotyl bromide (4784-77-4,29576-14-5,39616-19-8) + sodium ethyl acetylacetate enolate (1007476-32-5) → 2-acetyl-hex-4-enoic acid ethyl ester (29149-74-4)

Guidance literature:

With ethanol;

Reference yield:

(Z)-crotyl bromide (4784-77-4,29576-14-5,39616-19-8) + ethyl acetoacetate (141-97-9) → 2-acetyl-hex-4-enoic acid ethyl ester (29149-74-4)

Guidance literature:

ethyl acetoacetate; With sodium ethanolate; In ethanol; at 25 ℃; for 0.5h;

(Z)-crotyl bromide; In ethanol; Heating;

DOI:10.1080/10426500108046644

Reference yield:

ethyl acetoacetate (141-97-9) + (E)-crotyl methyl carbonate (103185-13-3) → 2-acetyl-hex-4-enoic acid ethyl ester (29149-74-4) + ethyl 2-acetyl-3-methyl-4-pentenoate (29149-73-3)

Guidance literature:

With N-methylcyclohexylamine; (η6-1,3,5-cyclooctatriene)(η4-1,5-cyclooctadiene)ruthenium(0); at 80 ℃; for 10h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/0022-328X(93)80158-8

upstream raw materials:

(E/Z)-crotyl bromide

ethyl acetoacetate

(E)-crotyl methyl carbonate

3-buten-2-yl methyl carbonate

Downstream raw materials:

hept-5-en-2-one

3-methylheptan-2-one