Uridine, 3'-deoxy-5-fluoro-

Base Information

• Chemical Name: Uridine, 3'-deoxy-5-fluoro-
• CAS No.: 18829-83-9
• Molecular Formula: C9H11FN2O5
• Molecular Weight: 246.195

Synonyms:5-Fluor-3'-desoxyuridin;5-fluoro-3'-deoxyuridine;3'-deoxy-5-fluorouridine;5-fluoro-3'-deoxy-uridine;1-(3-Deoxy-β-D-erythro-pentofuranosyl)-5-fluorouracil;

Chemical Property of Uridine, 3'-deoxy-5-fluoro-

Chemical Property:

• PSA: 104.55000
• LogP: -1.68360

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Uridine, 3'-deoxy-5-fluoro-

There total 3 articles about Uridine, 3'-deoxy-5-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-[(2-aminophenyl)acetyl]-2'-deoxy-5-fluorouridine (650629-23-5) → 2-oxoindole (59-48-3) + 5-Fluoro-3'-deoxyuridine (18829-83-9)

Guidance literature:

In phosphate buffer; at 37 ℃; pH=7.4;

DOI:10.1016/S0968-0896(03)00426-7

Reference yield:

5'-(3-(2-nitrophenyl)-2,2-dimethylpropionyl)-2'-deoxy-5-fluorouridine (650629-20-2) → 3,3-dimethyl-3,4-dihydroquinolin-2(1H)-one (92367-59-4) + 5-Fluoro-3'-deoxyuridine (18829-83-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; atmospheric pressure;

DOI:10.1016/S0968-0896(03)00426-7

Reference yield:

5'-[2-methyl-2-(2-nitrophenyl)propionyl]-2'-deoxy-5-fluorouridine (650629-18-8) → 3,3-dimethyloxindole (19155-24-9) + 5-Fluoro-3'-deoxyuridine (18829-83-9)

Guidance literature:

With sodium tetrahydroborate; palladium on activated charcoal; In methanol; water;

DOI:10.1016/S0968-0896(03)00426-7

upstream raw materials:

5'-[(2-aminophenyl)acetyl]-2'-deoxy-5-fluorouridine

5'-[2-methyl-2-(2-nitrophenyl)propionyl]-2'-deoxy-5-fluorouridine

5'-(3-(2-nitrophenyl)-2,2-dimethylpropionyl)-2'-deoxy-5-fluorouridine

Downstream raw materials:

5'-[(2-nitrophenyl)acetyl]-2'-deoxy-5-fluorouridine

5'-(3-(2-nitrophenyl)propionyl)-2'-deoxy-5-fluorouridine

5'-[2-methyl-2-(2-nitrophenyl)propionyl]-2'-deoxy-5-fluorouridine

5'-(3-(2-nitrophenyl)-2,2-dimethylpropionyl)-2'-deoxy-5-fluorouridine

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