(R)-(-)-benoxaprofen

Base Information

Chemical Name:(R)-(-)-benoxaprofen
CAS No.:70280-67-0
Molecular Formula:C₁₆H₁₂ClNO₃
Molecular Weight:301.729
Hs Code.:
UNII:261K1A3F0M
DSSTox Substance ID:DTXSID30220512
Wikidata:Q27254029

Synonyms:(R)-(-)-benoxaprofen;Benoxaprofen, (R)-;261K1A3F0M;70280-67-0;UNII-261K1A3F0M;(R)-benoxaprofen;SCHEMBL24414;DTXSID30220512;5-Benzoxazoleacetic acid, 2-(4-chlorophenyl)-alpha-methyl-, (R)-;Q27254029;5-BENZOXAZOLEACETIC ACID, 2-(4-CHLOROPHENYL)-.ALPHA.-METHYL-, (.ALPHA.R)-

Suppliers and Price of (R)-(-)-benoxaprofen

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-(-)-benoxaprofen

Chemical Property:

Vapor Pressure:9.61E-09mmHg at 25°C
Boiling Point:446.2°Cat760mmHg
Flash Point:223.6°C
Density:1.362g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:301.0505709
Heavy Atom Count:21
Complexity:384

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC2=C(C=C1)OC(=N2)C3=CC=C(C=C3)Cl)C(=O)O
Isomeric SMILES:C[C@H](C1=CC2=C(C=C1)OC(=N2)C3=CC=C(C=C3)Cl)C(=O)O

Technology Process of (R)-(-)-benoxaprofen

There total 17 articles about (R)-(-)-benoxaprofen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 87498-09-7
benoxaprofen methyl ester

: 51234-28-7,70280-67-0,66934-19-8
benoxaprofen

Guidance literature:: With potassium hydroxide; for 0.5h; Heating;
DOI:10.1021/jo00359a045

Reference yield:

: C₁₆H₁₂ClNO₂

: 51234-28-7,70280-67-0,66934-19-8
benoxaprofen

Guidance literature:: With hydrogenchloride; sodium chlorite; dihydrogen peroxide; potassium bromide; In water; acetonitrile; at 5 - 15 ℃; for 1h; pH=3.2;

Reference yield:

: 21850-61-3
2-(4-hydroxyphenyl)propanenitrile

: 51234-28-7,70280-67-0,66934-19-8
benoxaprofen

Guidance literature:: Multi-step reaction with 4 steps

1: HNO₃ / acetic acid

2: SnCl₂, aq. HCl / ethanol

3: Py

4: aq. HCl / 2.5 h / Heating

With pyridine; hydrogenchloride; nitric acid; tin(ll) chloride; In ethanol; acetic acid;
DOI:10.1021/jm00235a012