(3-amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone

Base Information

Chemical Name:(3-amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone
CAS No.:188782-68-5
Molecular Formula:C24H16N2OS2
Molecular Weight:412.52700
Hs Code.:2934999090
Mol file:188782-68-5.mol

Synonyms:(3-Amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone;

Suppliers and Price of (3-amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3-AMINO-6-PHENYL-4-(THIOPHEN-2-YL)THIENO[2,3-B]PYRIDIN-2-YL)(PHENYL)METHANONE 95.00%
5MG
$ 497.62

Total 7 raw suppliers

Chemical Property of (3-amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone

Chemical Property:

PSA：112.46000
Density:1.345
LogP:7.08620

Purity/Quality:

97% ^*data from raw suppliers

(3-AMINO-6-PHENYL-4-(THIOPHEN-2-YL)THIENO[2,3-B]PYRIDIN-2-YL)(PHENYL)METHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3-amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone

There total 10 articles about (3-amino-6-phenyl-4-(thiophen-2-yl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.2%

: 131841-89-9
3-cyano-6-phenyl-4-(2-thienyl)pyridin-2(1H)-thione

: 70-11-1
α-bromoacetophenone

: 188782-68-5
3-Amino-2-benzoyl-6-phenyl-4-(2-thienyl)-thieno[2,3-b]pyridine

Guidance literature:: With sodium methylate; In methanol; for 3h; Reflux;

Reference yield: 73.0%

: 276671-28-4
2-(2-oxo-2-phenyl-ethylsulfanyl)-6-phenyl-4-thiophen-2-yl-nicotinonitrile

: 188782-68-5
3-Amino-2-benzoyl-6-phenyl-4-(2-thienyl)-thieno[2,3-b]pyridine

Guidance literature:: With sodium ethanolate; In ethanol; Heating;

Reference yield:

: 131841-89-9
3-cyano-6-phenyl-4-(2-thienyl)pyridin-2(1H)-thione

: 188782-68-5
3-Amino-2-benzoyl-6-phenyl-4-(2-thienyl)-thieno[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / NaOMe / methanol / 3 h / Heating

2: 70 percent / 10 percent ethanolic KOH / 5 h / Heating

With potassium hydroxide; sodium methylate; In methanol; 1: Alkylation / 2: Cyclization;
DOI:10.1080/10426509808035673