Ethanamine, 2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-N-[2-[[(1,1-dimethylethyl)diphenyl silyl]oxy]ethyl]-

Base Information

• Chemical Name: Ethanamine, 2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-N-[2-[[(1,1-dimethylethyl)diphenyl silyl]oxy]ethyl]-
• CAS No.: 189279-33-2
• Molecular Formula: C36H47NO2Si2
• Molecular Weight: 581.946
• Mol file: 189279-33-2.mol

Synonyms:

Chemical Property of Ethanamine, 2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-N-[2-[[(1,1-dimethylethyl)diphenyl silyl]oxy]ethyl]-

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanamine, 2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-N-[2-[[(1,1-dimethylethyl)diphenyl silyl]oxy]ethyl]-

There total 2 articles about Ethanamine, 2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-N-[2-[[(1,1-dimethylethyl)diphenyl silyl]oxy]ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2'-iminobis[ethanol] (111-42-2) + tert-butylchlorodiphenylsilane (58479-61-1) → N,N-[bis(2-tert-butyldiphenylsilyloxyethyl)]amine (189279-33-2)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

DOI:10.1039/b201691e

Reference yield: 87.0%

→ N,N-[bis(2-tert-butyldiphenylsilyloxyethyl)]amine (189279-33-2)

Guidance literature:

Reference yield: 93.0%

(R)-(+)-trityl glycidyl ether (65291-30-7) + N,N-[bis(2-tert-butyldiphenylsilyloxyethyl)]amine (189279-33-2) → 3-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]-1-(triphenylmethoxy)-2-propanol (189279-34-3)

Guidance literature:

With lithium perchlorate; In ethanol; at 65 ℃; for 28h; Product distribution / selectivity;

upstream raw materials:

2,2'-iminobis[ethanol]

tert-butylchlorodiphenylsilane

Downstream raw materials:

(R)-tert-butyl 3-hydroxy-4-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]butyrate

3-[N,N-bis(2-tert-butyldiphenylsilyloxyethyl)amino]-1-(triphenylmethoxy)-2-propanol

Refernces

• 1、 Faissat, Ludovic,Chavis, Claude,Montero, Jean-Louis,Lucas, Marc. "Aminolysis of cyclic thioxocarbonate of (R,R)-di-tert-butyl tartrate: Efficient access to thio- and thiolcarbamates". . p. 1253 - 1259. Retrieved 2002.
• 2、 -. "METHODS AND COMPOSITIONS FOR THE EFFICIENT DELIVERY OF THERAPEUTIC AGENTS TO CELLS AND ANIMALS". Page/Page column 59-60; 6/17. . Retrieved 2008/06/13.