Ponasterone A

Base Information

Chemical Name:Ponasterone A
CAS No.:13408-56-5
Molecular Formula:C₂₇H₄₄O₆
Molecular Weight:464.643
Hs Code.:
UNII:84986BG3NG
DSSTox Substance ID:DTXSID0040595
Nikkaji Number:J15.367B
Wikidata:Q27103520
Metabolomics Workbench ID:34485
ChEMBL ID:CHEMBL549789
Mol file:13408-56-5.mol

Synonyms:2 beta,3 beta,14,20,22-pentahydroxy-5 beta- cholest-7-en-6-one;25-deoxy-20-ecdysone;25-deoxyecdysterone;25d20E;ponasterone A;ponasterone A, ponasterone B (2alpha,3alpha,5beta,22R)-isomer

Suppliers and Price of Ponasterone A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ponasterone A
1mg
$ 299.00

TRC
Ponasterone A
5mg
$ 700.00

TRC
Ponasterone A
1mg
$ 185.00

Sigma-Aldrich
Ponasterone A ≥65%
1mg
$ 79.80

Crysdot
Ponasterone A 95+%
5mg
$ 380.00

Cayman Chemical
Ponasterone A ≥95%
1mg
$ 49.00

Cayman Chemical
Ponasterone A ≥95%
5mg
$ 184.00

Cayman Chemical
Ponasterone A ≥95%
25mg
$ 735.00

Cayman Chemical
Ponasterone A ≥95%
10mg
$ 343.00

Biosynth Carbosynth
Ponasterone A
50 mg
$ 2100.00

Total 29 raw suppliers

Chemical Property of Ponasterone A

Chemical Property:

Appearance/Colour:White Solid
Vapor Pressure:4.19E-19mmHg at 25°C
Melting Point:259-260° (dec)
Refractive Index:1.582
Boiling Point:640.5 °C at 760 mmHg
PKA:14.13±0.70(Predicted)
Flash Point:355.2 °C
PSA：118.22000
Density:1.22 g/cm³
LogP:2.73910
Storage Temp.:−20°C
Solubility.:Methanol (Slightly, Sonicated), Pyridine (Slightly)
XLogP3:1.9
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:464.31378912
Heavy Atom Count:33
Complexity:823

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ponasterone A ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)CCC(C(C)(C1CCC2(C1(CCC3C2=CC(=O)C4C3(CC(C(C4)O)O)C)C)O)O)O
Isomeric SMILES:CC(C)CC[C@H]([C@@](C)([C@H]1CC[C@@]2([C@@]1(CC[C@H]3C2=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)C)O)O)O
Uses Ponasterone A is an Ecdysone analog. Ponasterone A has been used to induce the expression of human huntingtin (HTT).

Technology Process of Ponasterone A

There total 9 articles about Ponasterone A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 82413-55-6
25,26-didehydroponasterone A

: 13408-48-5,19338-77-3,78148-78-4,13408-56-5
ponasterone A

Guidance literature:: With sodium nitrite; palladium on activated charcoal; In ethanol; water; for 0.5h; under 760 Torr;
DOI:10.1016/S0040-4020(02)00580-X

Reference yield: 90.0%

: 26362-25-4
Stachysterone C

: 13408-48-5,19338-77-3,78148-78-4,13408-56-5
ponasterone A

Guidance literature:: With sodium nitrite; palladium on activated charcoal; In ethanol; water; for 0.416667h; under 760 Torr;
DOI:10.1016/S0040-4020(02)00580-X

Reference yield: 24.0%

: 14188-76-2
2,3:20,22-di-O-isopropylideneponasterone A

: 13408-48-5,19338-77-3,78148-78-4,13408-56-5
ponasterone A

: 20,22-acetonide of ponasterone A

Guidance literature:: 2,3:20,22-di-O-isopropylideneponasterone A; With acetic acid; at 20 ℃; for 1.5h;

With zinc(II) chloride; at 20 ℃; for 5h;
DOI:10.1023/A:1016547122573