N,N',2-triphenylpropanediamide

Base Information

• Chemical Name: N,N',2-triphenylpropanediamide
• CAS No.: 10256-14-1
• Molecular Formula: C21H18 N2 O2
• Molecular Weight: 330.386
• NSC Number: 106666
• DSSTox Substance ID: DTXSID80907700
• Nikkaji Number: J2.253.035F
• Wikidata: Q82876869
• Mol file: 10256-14-1.mol

Synonyms:N,N',2-triphenylpropanediamide;10256-14-1;NSC106666;Maybridge1_006407;Oprea1_480197;SCHEMBL14842551;HMS559L05;DTXSID80907700;NSC-106666;N~1~,N~3~,2-Triphenylpropanediimidic acid

Chemical Property of N,N',2-triphenylpropanediamide

Chemical Property:

• Boiling Point: 630.9°Cat760mmHg
• Flash Point: 230.6°C
• Density: 1.263g/cm³
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 330.136827821
• Heavy Atom Count: 25
• Complexity: 401

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C(=O)NC2=CC=CC=C2)C(=O)NC3=CC=CC=C3

Technology Process of N,N',2-triphenylpropanediamide

There total 9 articles about N,N',2-triphenylpropanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

aniline (62-53-3) + diethyl 2-phenylmalonate (83-13-6) → 4-hydroxy-3-phenyl-2(1H)-quinolone (14933-29-0) + N1,N3,2-triphenylmalonamide (10256-14-1)

Guidance literature:

at 220 - 270 ℃;

DOI:10.1016/j.tet.2013.10.092

Reference yield: 84.0%

anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide (76434-58-7) + aniline (62-53-3) → N1,N3,2-triphenylmalonamide (10256-14-1)

Guidance literature:

for 0.05h; microwave irradiation;

DOI:10.1002/jhet.5570420716

Reference yield:

phenyl-malonic acid bis-(N'-phenyl ureide) + aniline (62-53-3) → N1,N3,2-triphenylmalonamide (10256-14-1) + bis(diphenyl)urea (102-07-8)

Guidance literature:

at 160 ℃;

upstream raw materials:

N,N'-phenylmalonyl-bis-carbamic acid diethyl ester

aniline

diethyl 2-phenylmalonate

anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide

Downstream raw materials:

2,N-diphenylacetamide

aniline

2-Amino-2-phenylmalonsaeure-dianilid

1.1.3.3.-Tetra-phenylcarbamoyl-1.3-diphenyl-propan