1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid

Base Information

Chemical Name:1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid
CAS No.:40117-92-8
Molecular Formula:C15H19 N O4
Molecular Weight:277.32
Hs Code.:2933399090
NSC Number:167845
DSSTox Substance ID:DTXSID90304862
Nikkaji Number:J1.687.717D
Wikidata:Q82051133
Mol file:40117-92-8.mol

Synonyms:1-benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid;40117-92-8;NSC167845;Oprea1_356028;1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylicacid;SCHEMBL16579978;DTXSID90304862;NSC-167845;SB43777;FT-0712628

Suppliers and Price of 1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylicacid 95%
1g
$ 439.00

American Custom Chemicals Corporation
1-BENZYL-4-CARBOXYMETHYLPIPERIDINE-4-CARBOXYLIC ACID 95.00%
5MG
$ 496.71

Alichem
1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylicacid
1g
$ 470.00

Total 7 raw suppliers

Chemical Property of 1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid

Chemical Property:

Vapor Pressure:5.56E-10mmHg at 25°C
Boiling Point:478.9°Cat760mmHg
Flash Point:243.4°C
PSA：77.84000
Density:1.268g/cm³
LogP:1.76600
Storage Temp.:2-8°C
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:277.13140809
Heavy Atom Count:20
Complexity:355

Purity/Quality:

97% ^*data from raw suppliers

1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1(CC(=O)O)C(=O)O)CC2=CC=CC=C2

Technology Process of 1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid

There total 5 articles about 1-Benzyl-4-(carboxymethyl)piperidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 86945-27-9
1-benzyl-4-cyanomethylpiperidine-4-carbonitrile

: 40117-92-8
1-benzyl-4-carboxymethyl-piperidine-4-carboxylic acid

Guidance literature:: 1-benzyl-4-cyanomethylpiperidine-4-carbonitrile; With hydrogenchloride; at 100 ℃; for 72h; Sealed tube; Inert atmosphere;

Sealed tube;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 40117-92-8
1-benzyl-4-carboxymethyl-piperidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 20 °C

2: ethanol; H₂O / 18 h / Heating

3: conc. aq. HCl / 24 h / Heating

With hydrogenchloride; triethylamine; In ethanol; dichloromethane; water;
DOI:10.1016/S0960-894X(02)00095-1

Reference yield:

: 1463-52-1
ethyl 2-(1-benzylpiperidin-4-ylidene)-2-cyanoacetate

: 40117-92-8
1-benzyl-4-carboxymethyl-piperidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol; H₂O / 18 h / Heating

2: conc. aq. HCl / 24 h / Heating

With hydrogenchloride; In ethanol; water;
DOI:10.1016/S0960-894X(02)00095-1