Tetramethylammonium acetate

Base Information

• Chemical Name: Tetramethylammonium acetate
• CAS No.: 10581-12-1
• Molecular Formula: C4H12N^.C2H3O2
• Molecular Weight: 133.191
• Hs Code.: 29239000
• European Community (EC) Number: 234-179-3
• NSC Number: 97381
• DSSTox Substance ID: DTXSID1065132
• Mol file: 10581-12-1.mol

Synonyms:Tetramethylammonium acetate;10581-12-1;Tetramethyl ammonium acetate;Methanaminium, N,N,N-trimethyl-, acetate;Ammonium, tetramethyl-, acetate;tetramethylazanium;acetate;Tetramethylammonium acetate, tech grade;EINECS 234-179-3;NSC 97381;Methanaminium, N,N,N-trimethyl-, acetate (1:1);tetramethylammoniumacetate;tetramethylammonium acetate, tech. 90%;SCHEMBL106975;C4H12N.C2H3O2;DTXSID1065132;Tetramethylammonium Acetate 98%;NSC97381;MFCD00011630;NSC-97381;AKOS015837513;C4-H12-N.C2-H3-O2;Methanaminium,N,N-trimethyl-, acetate;CS-W011077;FS-4082;HY-W010361;FT-0652109;T1048;T1397;O12146;Tetramethylammonium Acetate (ca. 50% in Water);J-001484;J-524889

Chemical Property of Tetramethylammonium acetate

Chemical Property:

• Appearance/Colour: clear colorless to pale yellow solution
• Melting Point: 184 °C
• PSA: 40.13000
• LogP: -0.92140
• Storage Temp.: -20°C
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 133.110278721
• Heavy Atom Count: 9
• Complexity: 44.6

Purity/Quality:

99%min ^*data from raw suppliers

Tetramethylammonium Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)[O-].C[N+](C)(C)C
• Uses: Tetramethylammonium acetate is used as an intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. Further, it is used to prepare (1R,4S)-4-hydroxycyclopent-2-en-1-essigsaeure-methylester by reacting with 1,3-dimethyl-imidazolidin-2-one. In addition to this, it serves as an emulsifier, catalyst, sterilizer, antistatic and antiseptic agent.

Technology Process of Tetramethylammonium acetate

There total 5 articles about Tetramethylammonium acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.6%

tetramethyl ammoniumhydroxide (75-59-2,104422-11-9,123626-97-1,154636-59-6,195460-17-4,78017-87-5,93615-68-0,129654-61-1) + acetic acid (64-19-7,77671-22-8) → tetramethyl ammonium acetate (10581-12-1)

Guidance literature:

In methanol; at 40 ℃; for 4h;

Reference yield: 44.3%

ammonium acetate (631-61-8,92206-38-7) + carbonic acid dimethyl ester (616-38-6) → tetramethyl ammonium acetate (10581-12-1)

Guidance literature:

With 1-ethyl-3-methylimidazolium bromide; at 169.84 ℃; for 8h;

DOI:10.1039/b601343k

Reference yield: 44.3%

methylamine acetate (6998-30-7) + carbonic acid dimethyl ester (616-38-6) → tetramethyl ammonium acetate (10581-12-1)

Guidance literature:

With 1-ethyl-3-methylimidazolium bromide; at 169.84 ℃; for 8h;

DOI:10.1002/adsc.200600451

upstream raw materials:

ammonium acetate

carbonic acid dimethyl ester

methylamine acetate

tetramethyl ammoniumhydroxide

Downstream raw materials:

(-)-picrasin B acetate

6-(hydroxymethyl)benzopyrene

6-Acetoxymethylbenzpyren

((CH₃)4N)⁽¹⁺⁾*((B(C₆F₅)3)2CH₃COO)^(1-)=(CH₃)4N((B(C₆F₅)3)2CH₃COO)

Refernces

• 1、 -. "Therapeutic delivery of carbon monoxide". Page/Page column 12. . Retrieved 2010/05/13.
• 2、 Zheng, Zhuoqun,Wu, Tinghua,Zhou, Xiaoping. "The synthesis of quaternary ammonium salts from ammonium salts and dialkyl carbonate". . p. 1864 - 1865. Retrieved 2008/03/14.