Technology Process of Benzo[g]pteridine-2,4(3H,10H)-dione,
10-(6-hydroxyhexyl)-7,8-dimethyl-, 5-oxide
There total 2 articles about Benzo[g]pteridine-2,4(3H,10H)-dione,
10-(6-hydroxyhexyl)-7,8-dimethyl-, 5-oxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 98 percent / Et3N / 5 h / 110 °C
2: 63 percent / H2O; dioxane / 15 h / Heating
3: 94 percent / NaNO3 / acetic acid / 3 h / Ambient temperature
With
sodium nitrate; triethylamine;
In
1,4-dioxane; water; acetic acid;
DOI:10.1021/jo962361w
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine / 6 h / Reflux
2: water; 1,4-dioxane / 15 h / Reflux
3: acetic acid; sodium nitrite / 3 h / Darkness
With
acetic acid; triethylamine; sodium nitrite;
In
1,4-dioxane; water;
DOI:10.1002/open.201700144
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 90 percent / aq. dithiothreitol / ethanol / 0.33 h / Heating
2: 90 percent / H3PO3, 2,4,6-triisopropylbenzenesylfonyl chloride / pyridine / 15 h / Ambient temperature
3: 75 percent / 1-adamantanecarboxylic acid chloride / pyridine / 24 h
4: S8 / pyridine; CS2 / 24 h
5: aq. NH3 / 3 h
With
sulfur; ammonium hydroxide; phosphonic Acid; 2,4,6-triisopropylphenylsulfonyl chloride; 1-Adamantanecarbonyl chloride; diothiothreitol;
In
pyridine; carbon disulfide; ethanol;
DOI:10.1021/jo962361w
